SCHEMBL15746403

SCHEMBL15746403

COCOC(=O)C(CC(C)C)NC(=O)CC(=O)NC(CC(C)C)C(=O)OCOC(=O)C(CC(C)C)NC(=O)CC(C)=O

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 7/20 0.40
TAS1R1 Q7RTX1 7/20 0.40
BIRC2 Q13490 3/20 0.39
ALDH1A1 P00352 1/20 0.38
MME P08473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
POLB P06746 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
FOLH1 Q04609 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15746392 0.92 TAS1R3 (0.48) TAS1R3TAS1R1BIRC2MMESMN1; SMN2
SCHEMBL15745790 0.88 TAS1R3 (0.38) TAS1R3TAS1R1BIRC2ALDH1A1MME
SCHEMBL15746387 0.86 ALDH1A1 (0.39) TAS1R3TAS1R1BIRC2ALDH1A1MME
SCHEMBL15745789 0.84 TAS1R3 (0.35) TAS1R3TAS1R1BIRC2ALDH1A1MME
SCHEMBL14902192 0.84 TAS1R3 (0.54) TAS1R3TAS1R1BIRC2MMESMN1; SMN2
SCHEMBL27827937 0.84 TAS1R3 (0.54) TAS1R3TAS1R1BIRC2MMESMN1; SMN2
SCHEMBL15745786 0.83 TAS1R3 (0.35) TAS1R3TAS1R1BIRC2ALDH1A1MME
SCHEMBL15745785 0.82 TAS1R3 (0.34) TAS1R3TAS1R1BIRC2ALDH1A1MME
SCHEMBL14902193 0.81 L3MBTL1 (0.50) TAS1R3TAS1R1BIRC2ALDH1A1MME
SCHEMBL15745781 0.79 TAS1R3 (0.36) TAS1R3TAS1R1BIRC2ALDH1A1MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140147687-A1 BIOLOGICALLY ABSORBABLE COATING FOR IMPLANTABLE DEVICES BASED ON COPOLYMERS HAVING ESTER BONDS AND METHODS OF FABRICATING THE SAME ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2014-05-29 US disclosed