SCHEMBL14902193

SCHEMBL14902193

CCOC(=O)[C@H](CC(C)C)NC(=O)CC(C)=O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.50
PPID Q08752 1/20 0.47
TAS1R3 Q7RTX0 4/20 0.44
TAS1R1 Q7RTX1 4/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
BIRC2 Q13490 3/20 0.42
ALDH1A1 P00352 1/20 0.42
CAD P27708 1/20 0.39
MME P08473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3861350 0.86 PPID (0.50) L3MBTL1PPIDTAS1R3TAS1R1KMT2A
SCHEMBL3861349 0.86 PPID (0.50) L3MBTL1PPIDTAS1R3TAS1R1KMT2A
SCHEMBL14902192 0.86 TAS1R3 (0.54) TAS1R3TAS1R1POLBBIRC2MME
SCHEMBL27827937 0.86 TAS1R3 (0.54) TAS1R3TAS1R1POLBBIRC2MME
SCHEMBL9142172 0.84 PPID (0.48) L3MBTL1PPIDTAS1R3TAS1R1KMT2A
SCHEMBL21792020 0.84 PPID (0.48) L3MBTL1PPIDTAS1R3TAS1R1KMT2A
SCHEMBL9142170 0.84 PPID (0.48) L3MBTL1PPIDTAS1R3TAS1R1KMT2A
SCHEMBL21777305 0.84 PPID (0.48) L3MBTL1PPIDTAS1R3TAS1R1KMT2A
SCHEMBL16252939 0.84 KMT2A (0.57) L3MBTL1PPIDTAS1R3TAS1R1KMT2A
SCHEMBL5813383 0.84 ALDH1A1 (0.60) L3MBTL1PPIDTAS1R3TAS1R1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2016-10-27 US disclosed
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2016-10-27 US disclosed
US-9394324-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2016-07-19 US disclosed
US-9394324-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2016-07-19 US disclosed
US-20130109662-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2013-05-02 US disclosed
US-20130109662-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2013-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130109662-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias FECH, SDHB, SLC40A1 L3MBTL1 2282/4885PPID 242/4885TAS1R3 2683/4885
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias FECH, SDHB, SLC40A1 L3MBTL1 2282/4885PPID 242/4885TAS1R3 2683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.