Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.48 |
| ▸ | LPL | P06858 | 5/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747886 | 0.97 | DGAT1 (0.53) | DGAT1LIPGLPLHPGDSPIM1 | |
| SCHEMBL21125910 | 0.90 | DGAT1 (0.57) | DGAT1LIPGLPLHSD17B1HSD17B2 | |
| SCHEMBL18015663 | 0.85 | DGAT1 (0.59) | DGAT1LIPGLPLCYP11B1HSD17B1 | |
| SCHEMBL21390894 | 0.85 | DGAT1 (0.53) | DGAT1LIPGLPLIDO1BCHE | |
| SCHEMBL18015548 | 0.83 | LPL (0.66) | DGAT1LIPGLPLPIM1CYP11B1 | |
| SCHEMBL30841290 | 0.83 | LPL (0.66) | DGAT1LIPGLPLPIM1CYP11B1 | |
| SCHEMBL29688361 | 0.83 | DGAT1 (0.70) | DGAT1LIPGLPLCYP11B1 | |
| SCHEMBL30739 | 0.83 | DGAT1 (0.70) | DGAT1LIPGLPLCYP11B1 | |
| SCHEMBL15747808 | 0.82 | DGAT1 (0.69) | DGAT1LIPGLPLHPGDS | |
| SCHEMBL21290175 | 0.82 | DGAT1 (0.56) | DGAT1LIPGLPLMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |