Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | LPL | P06858 | 3/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 2/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21125910 | 0.88 | DGAT1 (0.57) | DGAT1LPLLIPG | |
| SCHEMBL2697886 | 0.84 | DGAT1 (0.67) | DGAT1SNCALPLLIPGNPC1 | |
| SCHEMBL29688083 | 0.84 | DGAT1 (0.67) | DGAT1SNCALPLLIPGNPC1 | |
| SCHEMBL18015663 | 0.83 | DGAT1 (0.59) | DGAT1LPLLIPG | |
| SCHEMBL21390894 | 0.83 | DGAT1 (0.53) | DGAT1KDM1ALPLLIPGCYP3A4 | |
| SCHEMBL15747744 | 0.82 | DGAT1 (0.52) | DGAT1LPLLIPGMAP4K4 | |
| SCHEMBL30739 | 0.81 | DGAT1 (0.70) | DGAT1LPLLIPG | |
| SCHEMBL29688361 | 0.81 | DGAT1 (0.70) | DGAT1LPLLIPG | |
| SCHEMBL15747886 | 0.80 | DGAT1 (0.53) | DGAT1LPLLIPGMAP4K4 | |
| SCHEMBL21290171 | 0.79 | TOP1 (0.46) | DGAT1KDM1ADYRK1ACLK4TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752512-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| EP-3601304-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2019158453-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |