Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747771 | 0.89 | GRIN2B (0.42) | MAPTHSD17B10SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL15747824 | 0.86 | LNPEP (0.43) | MAPTHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL15747831 | 0.84 | ADORA2A (0.47) | ALDH1A1ADORA2AADORA2BPOLBTMEM97 | |
| SCHEMBL31439287 | 0.83 | MAPT (0.42) | MAPTHSD17B10ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15747804 | 0.79 | MTOR (0.40) | TMEM97SIGMAR1HTR1AHRH2HRH1 | |
| SCHEMBL18998180 | 0.78 | GABRA1 (0.54) | HSD17B10ALDH1A1HPGDLMNAL3MBTL1 | |
| SCHEMBL15747839 | 0.76 | CA1 (0.44) | MAPTALDH1A1TMEM97SIGMAR1SMN1; SMN2 | |
| SCHEMBL975238 | 0.75 | NPSR1 (0.60) | MAPTALDH1A1TMEM97SIGMAR1SMN1; SMN2 | |
| SCHEMBL15747857 | 0.74 | CA1 (0.42) | MAPTALDH1A1TMEM97SIGMAR1SMN1; SMN2 | |
| SCHEMBL15747763 | 0.73 | PIK3CA (0.42) | ALDH1A1POLBSMN1; SMN2KDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014079364-A1 | IMIDAZOLONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | 北京富龙康泰生物技术有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |