Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 1.00 |
| ▸ | ADRA1D | P25100 | 2/20 | 1.00 |
| ▸ | ADRA1B | P35368 | 2/20 | 1.00 |
| ▸ | HTR1A | P08908 | 4/20 | 0.60 |
| ▸ | DRD2 | P14416 | 4/20 | 0.60 |
| ▸ | HTR7 | P34969 | 4/20 | 0.60 |
| ▸ | HTR6 | P50406 | 4/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25342544 | 0.99 | HTR2A (1.00) | HTR2AADRA1DADRA1BHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL29432933 | 0.99 | HTR2A (1.00) | HTR2AADRA1DADRA1BHTR1ADRD2 | |
| SCHEMBL15748164 | 0.88 | HTR2A (0.78) | HTR2AADRA1DADRA1BHTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL9383611 | 0.86 | HTR2A (0.78) | HTR2AADRA1DADRA1BHTR1ADRD2 | |
| SCHEMBL17103036 | 0.85 | HTR2A (0.73) | HTR2AADRA1DADRA1BHTR1ADRD2 | |
| SCHEMBL15748178 | 0.82 | HTR2A (0.70) | HTR2AADRA1DADRA1BHTR1ADRD2 | |
| SCHEMBL8831311 | 0.82 | HTR2A (0.70) | HTR2AADRA1DADRA1BHTR1ADRD2 | |
| SCHEMBL8419556 | 0.80 | HTR2A (0.67) | HTR2AADRA1DADRA1BHTR1ADRD2 | |
| SCHEMBL8831599 | 0.80 | HTR2A (0.67) | HTR2AADRA1DADRA1BHTR1ADRD2 | |
| SCHEMBL8831833 | 0.79 | HTR2A (0.67) | HTR2AADRA1DADRA1BHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119745881-A | Application of benzisothiazole compound or salt thereof in preparation of medicine for treating premature ejaculation | 原研港生命科学(上海)有限公司 | 2025-04-04 | — | — | CN | claimed |
| CN-119564689-A | Application of benzotriazole compound or salt thereof in treatment of ischemic cerebral apoplexy | 原研港(上海)医药有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119564690-A | Application of benzotriazole piperazine compound or salt thereof in preparation of pulmonary arterial hypertension treatment drug | 原研港(上海)医药有限公司 | 2025-03-07 | — | — | CN | claimed |
| US-9802929-B2 | Benzo five-membered nitrogen heterocyclic piperidine or piperazine derivatives and preparation methods and pharmaceutical compositions thereof | SHENYANG HAIWANG BIOTECHNOLOGY CO., LTD. (CN) | 2017-10-31 | — | — | US | claimed |
| US-9415047-B2 | Use of benzo five-membered nitrogen heterocyclic piperazine or piperidine derivatives | Liaoning Emmy Biological Pharmaceutical Co., Ltd. (CN) | 2016-08-16 | — | — | US | claimed |
| US-20160009703-A1 | BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERIDINE OR PIPERAZINE DERIVATIVES AND PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS THEREOF | LIAONING EMMY BIOLOGICAL PHARMACEUTICAL CO., LTD (CN) | 2016-01-14 | — | — | US | claimed |
| US-20150297586-A1 | USE OF BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERAZINE OR PIPERIDINE DERIVATIVES | Liaoning Emmy Biological Pharmaceutical Co., Ltd. (CN) | 2015-10-22 | — | — | US | claimed |
| EP-2924033-A1 | USE OF BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERAZINE OR PIPERIDINE DERIVATIVES | Liaoning Emmy Biological Pharmaceutical Co., Ltd (CN) | 2015-09-30 | — | — | EP | claimed |
| EP-2924032-A1 | BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERIDINE OR PIPERAZINE DERIVATIVES AND PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS THEREOF | Liaoning Emmy Biological Pharmaceutical Co., Ltd (CN) | 2015-09-30 | — | — | EP | claimed |
| CN-103833658-A | Benzotriazole-based piperazine compound as well as preparation method and pharmaceutical composition thereof | LIAONING BEILEI BIOLOG PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | claimed |
| CN-103833642-A | Use of benzo five-membered azaheterocyclyl piperazine derivatives | LIAONING BEILEI BIOLOG PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | claimed |
| US-12630545-B2 | Crystal of compound X7 hydrochloride and its preparation method and application | Wang, Peng (CN) | 2026-05-19 | — | — | US | disclosed |
| CN-119745881-A | Application of benzisothiazole compound or salt thereof in preparation of medicine for treating premature ejaculation | 原研港生命科学(上海)有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-119564689-A | Application of benzotriazole compound or salt thereof in treatment of ischemic cerebral apoplexy | 原研港(上海)医药有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-119564690-A | Application of benzotriazole piperazine compound or salt thereof in preparation of pulmonary arterial hypertension treatment drug | 原研港(上海)医药有限公司 | 2025-03-07 | — | — | CN | disclosed |
| EP-2924033-A1 | USE OF BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERAZINE OR PIPERIDINE DERIVATIVES | Liaoning Emmy Biological Pharmaceutical Co., Ltd (CN) | 2015-09-30 | — | — | EP | disclosed |
| CN-103833642-A | Use of benzo five-membered azaheterocyclyl piperazine derivatives | LIAONING BEILEI BIOLOG PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | disclosed |
| CN-103833658-A | Benzotriazole-based piperazine compound as well as preparation method and pharmaceutical composition thereof | LIAONING BEILEI BIOLOG PHARMACEUTICAL CO LTD | 2014-06-04 | — | — | CN | disclosed |
| WO-2014079154-A1 | BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERIDINE OR PIPERAZINE DERIVATIVES AND PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS THEREOF | 辽宁贝雷生物制药有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |
| WO-2014079155-A1 | USE OF BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERAZINE OR PIPERIDINE DERIVATIVES | 辽宁贝雷生物制药有限公司 (CN) | 2014-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150297586-A1 | USE OF BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERAZINE OR PIPERIDINE DERIVATIVES | P2RX5, TBXA2R, CYP3A5 | HTR2A 353/4885ADRA1D 82/4885ADRA1B 72/4885 |
| US-12630545-B2 | Crystal of compound X7 hydrochloride and its preparation method and application | TRPC7, TNNT2, TNNC1 | HTR2A 682/4885ADRA1D 24/4885ADRA1B 23/4885 |
| US-20160009703-A1 | BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERIDINE OR PIPERAZINE DERIVATIVES AND PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS THEREOF | CYP3A5, IL5, ABCC5 | HTR2A 521/4885ADRA1D 694/4885ADRA1B 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.