Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 14/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13978916 | 0.90 | PRKCZ (0.58) | PRKCZCYP11B2CYP11B1CYP3A4CYP1A2 | |
| SCHEMBL14461164 | 0.83 | PRKCZ (0.51) | PRKCZCYP11B2CYP11B1CYP3A4CYP1A2 | |
| SCHEMBL15763544 | 0.81 | PRKCZ (0.46) | PRKCZCYP11B2CYP11B1CYP3A4CYP1A2 | |
| SCHEMBL20873066 | 0.80 | PRKCZ (0.64) | PRKCZCYP11B2CYP11B1CYP3A4CYP1A2 | |
| SCHEMBL24662637 | 0.79 | PRKCZ (0.56) | PRKCZCYP11B2CYP11B1CYP3A4CYP1A2 | |
| SCHEMBL133949 | 0.78 | PRKCZ (0.50) | PRKCZCYP11B2CYP11B1CYP3A4CYP1A2 | |
| SCHEMBL29351773 | 0.76 | DHFR (0.43) | CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1680196 | 0.76 | DHFR (0.43) | CYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL24662630 | 0.76 | CYP11B1 (0.58) | PRKCZCYP11B2CYP11B1CYP3A4CYP1A2 | |
| SCHEMBL20128338 | 0.75 | PRKCZ (0.47) | PRKCZCYP11B2CYP11B1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9818951-B2 | Polycyclic compound and organic electronic device comprising the same | LG CHEM, LTD. (KR) | 2017-11-14 | — | — | US | disclosed |
| US-9818951-B2 | Polycyclic compound and organic electronic device comprising the same | LG CHEM, LTD. (KR) | 2017-11-14 | — | — | US | disclosed |
| US-20160329500-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME | LG CHEM LTD. (KR) | 2016-11-10 | — | — | US | disclosed |
| US-20160329500-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME | LG CHEM LTD. (KR) | 2016-11-10 | — | — | US | disclosed |
| US-9484539-B2 | Polycyclic compound and organic electronic device comprising the same | LG CHEM, LTD. (KR) | 2016-11-01 | — | — | US | disclosed |
| US-9484539-B2 | Polycyclic compound and organic electronic device comprising the same | LG CHEM, LTD. (KR) | 2016-11-01 | — | — | US | disclosed |
| US-20140151670-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2014-06-05 | — | — | US | disclosed |
| US-20140151670-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2014-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160329500-A1 | POLYCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME | PIEZO1, EED, ETV6 | PRKCZ 4442/4885CYP11B2 2837/4885CYP11B1 3299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.