SCHEMBL20128338

SCHEMBL20128338

c1ccc2c(-c3c4ccc5ccccc5c4nc4c3ccc3ccccc34)cncc2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 1/20 0.47
CYP11B2 P19099 12/20 0.46
CYP11B1 P15538 9/20 0.46
CYP17A1 P05093 3/20 0.46
CYP3A4 P08684 2/20 0.46
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2B6 P20813 1/20 0.43
CYP2C19 P33261 1/20 0.43
ERN1 O75460 1/20 0.41
MAPT P10636 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HPRT1 P00492 1/20 0.39
KCNA5 P22460 1/20 0.37
KCNH2 Q12809 1/20 0.37
ALDH1A1 P00352 1/20 0.37
CYP2A6 P11509 1/20 0.37
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13978916 0.83 PRKCZ (0.58) PRKCZCYP11B2CYP11B1CYP17A1CYP3A4
SCHEMBL15004435 0.82 DHFR (0.45) CYP1A2CYP2D6CYP2C9CYP2C19MAPT
SCHEMBL14461164 0.80 PRKCZ (0.51) PRKCZCYP11B2CYP11B1CYP17A1CYP3A4
SCHEMBL20873066 0.77 PRKCZ (0.64) PRKCZCYP11B2CYP11B1CYP17A1CYP3A4
SCHEMBL16438154 0.75 HPRT1 (0.52) CYP11B1CYP3A4CYP1A2CYP2D6CYP2C9
SCHEMBL26261972 0.75 PRKCZ (0.54) PRKCZCYP11B2CYP11B1CYP17A1CYP3A4
SCHEMBL15763545 0.75 PRKCZ (0.50) PRKCZCYP11B2CYP11B1CYP17A1CYP3A4
SCHEMBL15004492 0.74 HPRT1 (0.48) CYP3A4CYP1A2MAPTL3MBTL1HPRT1
SCHEMBL24662630 0.73 CYP11B1 (0.58) PRKCZCYP11B2CYP11B1CYP17A1CYP3A4
SCHEMBL24662637 0.72 PRKCZ (0.56) PRKCZCYP11B2CYP11B1CYP17A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10804467-B2 Method of manufacturing organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2020-10-13 US disclosed
US-20180130949-A1 METHOD OF MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-10 US disclosed
US-20180130949-A1 METHOD OF MANUFACTURING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-10 US disclosed