SCHEMBL471147

SCHEMBL471147

CC(C)(C)c1ccc(Nc2ccc(C(C)(C)c3ccccc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 3/20 0.55
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 4/20 0.52
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
ALOX12 P18054 4/20 0.48
L3MBTL1 Q9Y468 4/20 0.48
HSD17B10 Q99714 3/20 0.48
ALOX15 P16050 2/20 0.48
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
PTGS1 P23219 1/20 0.48
SLC6A2 P23975 1/20 0.48
MAPK1 P28482 1/20 0.48
PTGS2 P35354 1/20 0.48
HTR2B P41595 1/20 0.48
ABCG2 Q9UNQ0 1/20 0.46
HPGD P15428 2/20 0.45
KCNK9 Q9NPC2 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158574 0.94 NR3C2 (0.60) NR3C2ALDH1A1CYP3A4ESR1ESR2
SCHEMBL1576428 0.91 ALDH1A1 (0.59) NR3C2ALDH1A1CYP3A4ESR1ESR2
SCHEMBL22432523 0.91 TSHR (0.46) NR3C2CYP3A4ESR1ESR2HSD17B10
Diphenylamine SCHEMBL29287150 0.89 ALDH1A1 (0.62) ALDH1A1CYP3A4ALOX12L3MBTL1HSD17B10
SCHEMBL502030 0.89 ALDH1A1 (0.62) ALDH1A1CYP3A4ALOX12L3MBTL1HSD17B10
SCHEMBL8626323 0.89 ALDH1A1 (0.62) NR3C2ALDH1A1CYP3A4ESR1ESR2
SCHEMBL18531361 0.87 ESR1 (0.65) NR3C2ALDH1A1CYP3A4ESR1ESR2
SCHEMBL14571901 0.86 HPGD (0.65) NR3C2ALDH1A1CYP3A4ESR1ESR2
SCHEMBL2392625 0.84 TSHR (0.52) ALDH1A1ALOX12L3MBTL1HSD17B10ALOX15
SCHEMBL49741 0.84 TSHR (0.52) ALDH1A1ALOX12L3MBTL1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8785534-B2 Use of polyamides that are resistant to corrosion and stress cracking BASF SE (DE) 2014-07-22 US disclosed
US-8785534-B2 Use of polyamides that are resistant to corrosion and stress cracking BASF SE (DE) 2014-07-22 US disclosed
EP-2553021-B1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2014-05-07 EP disclosed
US-8481652-B2 Thermoplastic polyamides having polyether amines BASF SE (DE) 2013-07-09 US disclosed
US-8481652-B2 Thermoplastic polyamides having polyether amines BASF SE (DE) 2013-07-09 US disclosed
US-20130023613-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-01-24 US disclosed
US-20130023613-A1 USE OF POLYAMIDES THAT ARE RESISTANT TO CORROSION AND STRESS CRACKING BASF SE (DE) 2013-01-24 US disclosed
US-8197715-B2 Thermoplastic moulding compositions having improved ductility BASE SE (DE) 2012-06-12 US disclosed
US-8197715-B2 Thermoplastic moulding compositions having improved ductility BASE SE (DE) 2012-06-12 US disclosed
EP-2257597-B1 POLYAMIDE NANOCOMPOSITES WITH HYPER- BRANCHED POLYETHERAMINES BASF SE (DE) 2011-11-30 EP disclosed
US-20100090174-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING IMPROVED DUCTILITY BASF SE (DE) 2010-04-15 US disclosed
US-20100090174-A1 THERMOPLASTIC MOULDING COMPOSITIONS HAVING IMPROVED DUCTILITY BASF SE (DE) 2010-04-15 US disclosed
WO-2010028975-A2 THERMALLY CONDUCTIVE POLYAMIDE HAVING INCREASED FLOW CAPABILITY BASF SE (DE) 2010-03-18 WO disclosed
EP-2049597-B1 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2010-02-24 EP disclosed
US-20100019210-A1 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2010-01-28 US disclosed
WO-2009115535-A2 POLYAMIDE NANOCOMPOSITES WITH HYPER- BRANCHED POLYETHERAMINES BASF SE (DE) 2009-09-24 WO disclosed
WO-2009115536-A1 POLYAMIDE NANOCOMPOSITES WITH HYPER-BRANCHED POLYETHYLENIMINES BASF SE (DE) 2009-09-24 WO disclosed
WO-2009077492-A2 THERMOPLASTIC POLYAMIDES HAVING POLYETHER AMINES BASF SE (DE) 2009-06-25 WO disclosed
WO-2008074687-A2 THERMOPLASTIC MOULDING COMPOSITIONS HAVING IMPROVED DUCTILITY BASF SE (DE) 2008-06-26 WO disclosed
WO-2008012233-A2 THERMOPLASTIC MOULDING COMPOSITIONS WITH HIGH STIFFNESS BASF SE (DE) 2008-01-31 WO disclosed