Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15764472 | 0.85 | ALDH1A1 (0.45) | KIF11 | |
| SCHEMBL15764481 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL15764466 | 0.79 | ALDH1A1 (0.32) | — | |
| SCHEMBL4457146 | 0.74 | — | — | |
| SCHEMBL4457143 | 0.74 | — | — | |
| SCHEMBL2546539 | 0.73 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL29400681 | 0.73 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL5967574 | 0.73 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL4455551 | 0.71 | KDM4E (0.38) | — | |
| SCHEMBL4455547 | 0.71 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133141-B2 | Cysteine and cystine bioisosteres to treat schizophrenia and reduce drug cravings | MARQUETTE UNIVERSITY (US) | 2015-09-15 | — | — | US | disclosed |
| US-20140155440-A1 | CYSTEINE AND CYSTINE BIOISOSTERES TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS | MARQUETTE UNIVERSITY (US) | 2014-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155440-A1 | CYSTEINE AND CYSTINE BIOISOSTERES TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS | CTH, CBS, SLC7A11 | KIF11 4028/4885DNMT1 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.