Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20079622 | 0.81 | ALDH1A1 (0.41) | CA2CA1ALDH1A1LMNAMAPT | |
| SCHEMBL17325863 | 0.81 | ALDH1A1 (0.41) | CA2CA1ALDH1A1LMNAMAPT | |
| SCHEMBL20079589 | 0.80 | ALDH1A1 (0.40) | CA2CA1ALDH1A1LMNAMAPT | |
| SCHEMBL21554140 | 0.79 | LMNA (0.42) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL17322685 | 0.77 | ALDH1A1 (0.38) | CA2CA1ALDH1A1LMNAMAPT | |
| SCHEMBL13224653 | 0.77 | LMNA (0.45) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL17322682 | 0.77 | ALDH1A1 (0.38) | CA2CA1ALDH1A1LMNAMAPT | |
| SCHEMBL17322684 | 0.76 | ALDH1A1 (0.38) | CA2CA1ALDH1A1LMNAMAPT | |
| SCHEMBL12974566 | 0.75 | ENPP2 (0.41) | CA2CA1MAPTHDAC1HDAC6 | |
| SCHEMBL119010 | 0.74 | LMNA (0.44) | CA2CA1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014084372-A1 | POLYPEPTIDE AND IMAGING METHOD | 国立大学法人京都大学 (JP) | 2014-06-05 | — | — | WO | disclosed |