Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPOR | P19235 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28137098 | 0.86 | MEN1 (0.44) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL1577179 | 0.86 | MEN1 (0.44) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL19138470 | 0.84 | SLC1A1 (0.49) | ALOX5SLC1A1MAOBALDH1A1CA1 | |
| SCHEMBL1576833 | 0.83 | MEN1 (0.41) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL1576866 | 0.81 | KMT2A (0.47) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL1895976 | 0.79 | KMT2A (0.45) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL7772290 | 0.78 | LMNA (0.52) | MEN1KMT2AALDH1A1L3MBTL1LMNA | |
| SCHEMBL19836930 | 0.75 | SLC1A1 (0.51) | SLC1A1MAOBKMT2AALDH1A1CA1 | |
| SCHEMBL6813227 | 0.75 | KMT2A (0.54) | ALOX5PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL19836929 | 0.75 | SLC1A1 (0.51) | SLC1A1MAOBKMT2AALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853439-B2 | Processes for the preparation of lacosamide and intermediates thereof | CADILA HEALTHCARE LIMITED (IN) | 2014-10-07 | — | — | US | claimed |
| US-20120209022-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2012-08-16 | — | — | US | claimed |
| EP-2480524-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | Cadila Healthcare Limited (IN) | 2012-08-01 | — | — | EP | claimed |
| WO-2011039781-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2011-04-07 | — | — | WO | claimed |
| US-9242926-B2 | Processes for the preparation of lacosamide and intermediates thereof | CADILA HEALTHCARE LIMITED (IN) | 2016-01-26 | — | — | US | disclosed |
| US-8853439-B2 | Processes for the preparation of lacosamide and intermediates thereof | CADILA HEALTHCARE LIMITED (IN) | 2014-10-07 | — | — | US | disclosed |
| US-20140296572-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2014-10-02 | — | — | US | disclosed |
| US-20120209022-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2012-08-16 | — | — | US | disclosed |
| EP-2480524-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | Cadila Healthcare Limited (IN) | 2012-08-01 | — | — | EP | disclosed |
| WO-2011039781-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2011-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120209022-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CA3, TREH, NAAA | ALOX5 1446/4885PTGS1 2129/4885PTGS2 1860/4885 |
| US-20140296572-A1 | PROCESSES FOR THE PREPARATION OF LACOSAMIDE AND INTERMEDIATES THEREOF | CA3, TREH, NAAA | ALOX5 1446/4885PTGS1 2129/4885PTGS2 1860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.