Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576650 | 0.82 | NPC1 (0.62) | NPC1RAB9AALDH1A1MAPK1NUDT1 | |
| SCHEMBL1576997 | 0.79 | NUDT1 (0.52) | NPC1RAB9AALDH1A1NUDT1POLB | |
| SCHEMBL2800474 | 0.77 | NPC1 (0.57) | NPC1RAB9AALDH1A1MAPK1NUDT1 | |
| SCHEMBL1576638 | 0.76 | NUDT1 (0.65) | NUDT1KDM4EKMT2ASMN1; SMN2PDPK1 | |
| SCHEMBL18134205 | 0.76 | NUDT1 (0.66) | NPC1RAB9AALDH1A1MAPK1NUDT1 | |
| SCHEMBL8630748 | 0.76 | NPC1 (0.56) | NPC1RAB9AALDH1A1MAPK1NUDT1 | |
| SCHEMBL8446516 | 0.74 | NPC1 (0.54) | NPC1RAB9AALDH1A1MAPK1NUDT1 | |
| SCHEMBL1576783 | 0.74 | SMN1; SMN2 (0.55) | NPC1RAB9AALDH1A1MAPK1NUDT1 | |
| SCHEMBL8873952 | 0.74 | NUDT1 (0.46) | NUDT1KDM4EKMT2APDPK1TGFBR1 | |
| SCHEMBL6395516 | 0.73 | FGFR1 (0.37) | NUDT1POLBPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011039276-A1 | OXATHIAZINYL(HET)ARYLSULFONYLUREAS, PROCESSES AND INTERMEDIATES FOR PREPARATION THEREOF AND USE THEREOF AS CROP PROTECTION AGENTS AND CROP GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2011-04-07 | — | — | WO | disclosed |
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| US-5580842-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| US-5476936-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-19 | — | — | US | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |