SCHEMBL2800474

SCHEMBL2800474

CCOc1cc(N)nc(N)n1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
ALDH1A1 P00352 1/20 0.57
MAPK1 P28482 1/20 0.57
NUDT1 P36639 3/20 0.44
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 4/20 0.40
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.40
LMNA P02545 1/20 0.40
DYRK1A Q13627 1/20 0.37
TLR8 Q9NR97 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6768514 0.89 RAB9A (0.49) NPC1RAB9AALDH1A1MAPK1NUDT1
SCHEMBL1576650 0.89 NPC1 (0.62) NPC1RAB9AALDH1A1MAPK1NUDT1
SCHEMBL10398846 0.82 CDK1 (0.43) NPC1RAB9AALDH1A1MAPK1NUDT1
SCHEMBL8630748 0.82 NPC1 (0.56) NPC1RAB9AALDH1A1MAPK1NUDT1
SCHEMBL20606895 0.82 ALDH1A1 (0.44) NPC1RAB9AALDH1A1MAPK1POLB
SCHEMBL18134205 0.82 NUDT1 (0.66) NPC1RAB9AALDH1A1MAPK1NUDT1
SCHEMBL11831023 0.82 ALDH1A1 (0.44) NPC1RAB9AALDH1A1MAPK1POLB
SCHEMBL8446516 0.80 NPC1 (0.54) NPC1RAB9AALDH1A1MAPK1NUDT1
SCHEMBL1576783 0.80 SMN1; SMN2 (0.55) NPC1RAB9AALDH1A1MAPK1NUDT1
SCHEMBL16463790 0.79 CDK1 (0.43) NPC1RAB9AALDH1A1MAPK1NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026097624-A1 METHOD FOR PREPARING CHLORINE-RESISTANT NANOFILTRATION MEMBRANE, AND CHLORINE-RESISTANT NANOFILTRATION MEMBRANE PREPARED THEREWITH 沃顿科技股份有限公司 2026-05-15 WO claimed
CN-122006472-A Preparation method of chlorine-resistant nanofiltration membrane and chlorine-resistant nanofiltration membrane prepared by preparation method 沃顿科技股份有限公司 2026-05-12 CN claimed
CN-119875059-A Thermoplastic polyurethane foam material 万华化学集团股份有限公司 2025-04-25 CN claimed
CN-111718461-B Thermoplastic polyurethane elastic fiber and preparation method thereof 浙江华峰热塑性聚氨酯有限公司 2022-06-21 CN claimed
CN-111718461-A Thermoplastic polyurethane elastic fiber and preparation method thereof 浙江华峰热塑性聚氨酯有限公司 2020-09-29 CN claimed
WO-2026097624-A1 METHOD FOR PREPARING CHLORINE-RESISTANT NANOFILTRATION MEMBRANE, AND CHLORINE-RESISTANT NANOFILTRATION MEMBRANE PREPARED THEREWITH 沃顿科技股份有限公司 2026-05-15 WO disclosed
CN-122006472-A Preparation method of chlorine-resistant nanofiltration membrane and chlorine-resistant nanofiltration membrane prepared by preparation method 沃顿科技股份有限公司 2026-05-12 CN disclosed
CN-119875059-A Thermoplastic polyurethane foam material 万华化学集团股份有限公司 2025-04-25 CN disclosed
CN-111718461-B Thermoplastic polyurethane elastic fiber and preparation method thereof 浙江华峰热塑性聚氨酯有限公司 2022-06-21 CN disclosed
CN-111718461-A Thermoplastic polyurethane elastic fiber and preparation method thereof 浙江华峰热塑性聚氨酯有限公司 2020-09-29 CN disclosed
EP-2035419-B1 5-ARYL-SUBSTITUTED DIHYDROPYRIDOPYRIMIDINES AND DIHYDROPYRIDAZINES AND USE THEREOF AS MINERAL CORTICOID ANTAGONISTS BAYER IP GMBH (DE) 2016-06-22 EP disclosed
EP-2035419-B1 5-ARYL-SUBSTITUTED DIHYDROPYRIDOPYRIMIDINES AND DIHYDROPYRIDAZINES AND USE THEREOF AS MINERAL CORTICOID ANTAGONISTS BAYER IP GMBH (DE) 2016-06-22 EP disclosed
US-20060189620-A1 Immunosuppressive effects of pteridine derivatives 4 AZA BIOSCIENCE NV (BE) 2006-08-24 US disclosed
EP-1663244-A2 PTERIDINE DERIVATIVES FOR THE TREATMENT OF SEPTIC SHOCK AND TNF-ALPHA-RELATED DISEASES. 4 AZA Bioscience nv (BE) 2006-06-07 EP disclosed
EP-1658081-A2 IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES 4 AZA Bioscience nv (BE) 2006-05-24 EP disclosed
EP-1594902-A1 MOLECULARY IMPRINTED POLYMERS FOR EXTRACTION OF COMPONENTS FROM FOODSTRUFFS MIP Technologies AB (SE) 2005-11-16 EP disclosed
WO-2005025574-A2 PTERIDINE DERIVATIVES FOR THE TREATMENT OF SEPTIC SHOCK AND TNF-α-RELATED DISEASES. 4 AZA BIOSCIENCE NV (BE) 2005-03-24 WO disclosed
WO-2005021003-A2 IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES 4 AZA BIOSCIENCE NV (BE) 2005-03-10 WO disclosed
WO-2004067578-A1 MOLECULARY IMPRINTED POLYMERS FOR EXTRACTION OF COMPONENTS FROM FOODSTRUFFS MIP TECHNOLOGIES AB (SE) 2004-08-12 WO disclosed
US-20040077859-A1 Immunosuppressive effects of pteridine derivatives 4 AZA BIOSCIENCE NV (BE) 2004-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077859-A1 Immunosuppressive effects of pteridine derivatives TPMT, NFATC1, MALT1 NPC1 1701/4885RAB9A 1698/4885ALDH1A1 1257/4885
US-20060189620-A1 Immunosuppressive effects of pteridine derivatives TPMT, NFATC1, MALT1 NPC1 1701/4885RAB9A 1698/4885ALDH1A1 1257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.