Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576650 | 0.86 | NPC1 (0.62) | NPC1RAB9AALDH1A1MAPK1KMT2A | |
| SCHEMBL9340477 | 0.85 | KMT2A (0.45) | NPC1RAB9AALDH1A1MAPK1KMT2A | |
| SCHEMBL9340530 | 0.81 | CDK1 (0.43) | NPC1RAB9AALDH1A1MAPK1KMT2A | |
| SCHEMBL17581241 | 0.80 | KMT2A (0.44) | NPC1RAB9AALDH1A1MAPK1KMT2A | |
| SCHEMBL2800474 | 0.80 | NPC1 (0.57) | NPC1RAB9AALDH1A1MAPK1NUDT1 | |
| SCHEMBL8630748 | 0.78 | NPC1 (0.56) | NPC1RAB9AALDH1A1MAPK1NUDT1 | |
| SCHEMBL18134205 | 0.78 | NUDT1 (0.66) | NPC1RAB9AALDH1A1MAPK1NUDT1 | |
| SCHEMBL10618233 | 0.78 | NPC1 (0.51) | NPC1RAB9AALDH1A1MAPK1NUDT1 | |
| SCHEMBL8448250 | 0.78 | KMT2A (0.51) | NPC1RAB9AALDH1A1KMT2ANUDT1 | |
| SCHEMBL17589003 | 0.78 | HTR7 (0.46) | KMT2ANUDT1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628031-B1 | HERBICIDE N- (PYRIMIDIN-2-YL)AMINOCARBONYL] BENZENE SULPHONAMIDES | BASF AG (DE) | 1999-06-16 | — | — | EP | disclosed |
| US-5612286-A | FLUORINE SUBSTITUTED HEERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-18 | — | — | US | disclosed |
| EP-0628031-A1 | HERBICIDE N- (PYRIMIDIN-2-YL)AMINOCARBONYL] BENZENE SULPHONAMIDES | BASF Aktiengesellschaft (DE) | 1994-12-14 | — | — | EP | disclosed |
| EP-0378089-B1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AG (DE) | 1994-06-29 | — | — | EP | disclosed |
| EP-0378092-B1 | Herbicidal sulfonyl ureas, process for preparing them and their use | BASF AG (DE) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993016998-A1 | HERBICIDE N-[(PYRIMIDIN-2-YL)AMINOCARBONYL] BENZENE SULPHONAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-02 | — | — | WO | disclosed |
| US-5011927-A | Preparation of 2-amino-4-fluoropyrimidine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| EP-0378089-A1 | Method for the preparation of 2-amino-4-fluoropyrimidine derivatives | BASF Aktiengesellschaft (DE) | 1990-07-18 | — | — | EP | disclosed |
| EP-0378092-A1 | Herbicidal sulfonyl ureas, process for preparing them and their use | BASF Aktiengesellschaft (DE) | 1990-07-18 | — | — | EP | disclosed |