SCHEMBL1576926

SCHEMBL1576926

CC(C)(C)OC(=O)C(C)(C)C(=O)SCCO

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.45
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15625124 0.82 DGAT1 (0.42) DGAT1
SCHEMBL17635362 0.79 CYP4F2 (0.43)
SCHEMBL10819867 0.78 DGAT1 (0.39) DGAT1
SCHEMBL15468707 0.75 TSHR (0.32)
SCHEMBL3072338 0.72 TDP1 (0.32) TDP1
SCHEMBL3141601 0.71 DGAT1 (0.79) DGAT1TDP1
SCHEMBL5823532 0.69
SCHEMBL9107639 0.69 DGAT1 (0.36) DGAT1TDP1
SCHEMBL2514266 0.69 TDP1 (0.35) TDP1
SCHEMBL16647560 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2307434-B1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS IDENIX PHARMACEUTICALS INC (US) 2014-02-12 EP disclosed
EP-2307434-B1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS IDENIX PHARMACEUTICALS INC (US) 2014-02-12 EP disclosed
EP-2476690-A1 Compounds and pharmaceutical compositions for the treatment of viral infections IDENIX Pharmaceuticals, Inc. (US) 2012-07-18 EP disclosed
EP-2476690-A1 Compounds and pharmaceutical compositions for the treatment of viral infections IDENIX Pharmaceuticals, Inc. (US) 2012-07-18 EP disclosed
EP-2307434-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS IDENIX Pharmaceuticals, Inc. (US) 2011-04-13 EP disclosed
WO-2010014134-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS IDENIX PHARAMACEUTICALS, INC. (US) 2010-02-04 WO disclosed
WO-2010014134-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS IDENIX PHARAMACEUTICALS, INC. (US) 2010-02-04 WO disclosed
US-20100003217-A1 Compounds and Pharmaceutical Compositions for the Treatment of Viral Infections CRETTON-SCOTT ERIKA 2010-01-07 US disclosed
US-20100003217-A1 Compounds and Pharmaceutical Compositions for the Treatment of Viral Infections CRETTON-SCOTT ERIKA 2010-01-07 US disclosed
US-20100003217-A1 Compounds and Pharmaceutical Compositions for the Treatment of Viral Infections CRETTON-SCOTT ERIKA 2010-01-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100003217-A1 Compounds and Pharmaceutical Compositions for the Treatment of Viral Infections HAVCR2, PYGL, GOT1 DGAT1 926/4885TDP1 2616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.