Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 4/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15625124 | 0.81 | DGAT1 (0.42) | — | |
| SCHEMBL1576926 | 0.79 | DGAT1 (0.45) | — | |
| SCHEMBL1562023 | 0.75 | ALDH1A1 (0.50) | CYP4F2CYP4A11PKMKDM4EMMP8 | |
| SCHEMBL15468707 | 0.74 | TSHR (0.32) | ALDH1A1TSHRCYP2D6 | |
| Hydrochloric Acid SCHEMBL5446995 | 0.73 | ALDH1A1 (0.48) | CYP4F2CYP4A11PKMKDM4EMMP8 | |
| SCHEMBL15634844 | 0.71 | CYP4F2 (0.35) | CYP4F2CYP4A11KMT2ATSHRMGAM | |
| SCHEMBL2443587 | 0.71 | SOAT1 (0.44) | CYP4F2CYP4A11PKMKDM4EMMP8 | |
| Butane SCHEMBL11358505 | 0.71 | ALDH1A1 (0.46) | CYP4F2CYP4A11PKMKDM4EMMP8 | |
| SCHEMBL3072338 | 0.71 | TDP1 (0.32) | — | |
| SCHEMBL12149865 | 0.70 | RIPK1 (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852605-B1 | 3',5'-CYCLIC PHOSPHATE PRODRUGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-01-31 | — | — | EP | disclosed |
| US-9296778-B2 | 3′,5′-cyclic phosphate prodrugs for HCV infection | IDENIX PHARMACEUTICALS, INC. (US) | 2016-03-29 | — | — | US | disclosed |
| US-9296778-B2 | 3′,5′-cyclic phosphate prodrugs for HCV infection | IDENIX PHARMACEUTICALS, INC. (US) | 2016-03-29 | — | — | US | disclosed |