SCHEMBL1576936

SCHEMBL1576936

CC(C)(C)COC(=O)C(=CC=C(c1ccccc1)c1ccccc1)C(=O)OCC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
MAPK1 P28482 1/20 0.40
HIF1A Q16665 1/20 0.40
ALDH1A1 P00352 5/20 0.38
TDP1 Q9NUW8 4/20 0.38
HTR1A P08908 1/20 0.38
CYP2D6 P10635 1/20 0.38
SCN1A P35498 1/20 0.38
SLC6A3 Q01959 1/20 0.38
SCN5A Q14524 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
PRSS1 P07477 1/20 0.37
CTSG P08311 1/20 0.37
CTRB1 P17538 1/20 0.37
CMA1 P23946 1/20 0.37
POLB P06746 1/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14156332 0.83 MEN1 (0.60) KMT2AMEN1MAPK1ALDH1A1TDP1
SCHEMBL4849410 0.80 KMT2A (0.33) KMT2AMEN1MAPK1HIF1AALDH1A1
SCHEMBL12320346 0.80 TDP1 (0.42) KMT2AMEN1MAPK1ALDH1A1TDP1
SCHEMBL14135780 0.79 MEN1 (0.55) KMT2AMEN1ALDH1A1TDP1POLB
SCHEMBL1576779 0.79 ALDH1A1 (0.50) KMT2AMEN1ALDH1A1TDP1MTNR1A
SCHEMBL14017683 0.79 KMT2A (0.41) KMT2AMEN1MAPK1HIF1AALDH1A1
SCHEMBL12663178 0.78 KMT2A (0.67) KMT2AMEN1MAPK1ALDH1A1POLB
SCHEMBL1576590 0.77 TSHR (0.48) MTNR1AMTNR1BTSHRLMNAMAPT
SCHEMBL13515676 0.77 MEN1 (0.57) KMT2AMEN1MAPK1ALDH1A1TDP1
SCHEMBL12909852 0.77 KMT2A (0.39) KMT2AMEN1MAPK1HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022138480-A1 O/W TYPE EMULSION COMPOSITION CONTAINING POLYMER 住友精化株式会社 2022-06-30 WO disclosed
WO-2022138482-A1 POLYMER-CONTAINING O/W-TYPE EMULSION COMPOSITION 住友精化株式会社 2022-06-30 WO disclosed
WO-2022138481-A1 POLYMER-CONTAINING O/W EMULSION COMPOSITION 住友精化株式会社 2022-06-30 WO disclosed
EP-2683351-B1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME OREAL (FR) 2019-10-16 EP disclosed
EP-2266531-B1 Cosmetic composition comprising a superabsorbent polymer and an organic UV filter L'ORÉAL (FR) 2017-06-14 EP disclosed
EP-2538914-B1 COSMETIC COMPOSITION COMPRISING A SUPERABSORBENT POLYMER AND AT LEAST A GEMINI SURFACTANT ORÉAL L (FR) 2016-06-15 EP disclosed
US-9364690-B2 Composition comprising a superabsorbent polymer and a gemini surfactant L'OREAL (FR) 2016-06-14 US disclosed
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME OREAL (FR) 2016-03-10 US disclosed
US-20150224046-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT L'OREAL (FR) 2015-08-13 US disclosed
EP-2482793-B1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT ORÉAL L (FR) 2015-04-22 EP disclosed
EP-1468669-B1 An aqueous, sunscreen composition comprising at least a di- or tribloc copolymer and 4,4-diarylbutadien, and use thereof OREAL (FR) 2007-03-28 EP disclosed
EP-1468670-B1 Ein Lichtschutzmittel, welches mindestens ein Akrylamido-2-methylpropan sulfonsäure Polymer und 4,4-Diarylbutadien enthält, und die Verwendung davon OREAL (FR) 2007-01-24 EP disclosed
US-20060076542-A1 UV absorber mixture with affinity for textile fiber BASF AKTIENGESELLSCHAFT (DE) 2006-04-13 US disclosed
US-7011772-B2 UV absorbing mixture with textile fiber affinity BASF AKTIENGESELLSCHAFT (DE) 2006-03-14 US disclosed
EP-1267820-B1 UV-ABSORBING MIXTURE WITH TEXTILE FIBRE AFFINITY BASF AG (DE) 2005-11-02 EP disclosed
US-20040074012-A1 Method for providing textile material with uv protection BASF AKTIENGESELLSCHAFT (DE) 2004-04-22 US disclosed
EP-1383952-A2 METHOD FOR PROVIDING TEXTILE MATERIAL WITH UV PROTECTION BASF AKTIENGESELLSCHAFT (DE) 2004-01-28 EP disclosed
US-20030127633-A1 Uv absorbing mixture with textile fiber affinity BASF AKTIENGESELLSCHAFT (DE) 2003-07-10 US disclosed
EP-1258481-A1 Enaminotriazines as UV filters BASF AKTIENGESELLSCHAFT (DE) 2002-11-20 EP disclosed
WO-2002063091-A2 METHOD FOR PROVIDING TEXTILE MATERIAL WITH UV PROTECTION BASF AKTIENGESELLSCHAFT (DE) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150224046-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT KRT18, FABP2, FABP4 KMT2A 2861/4885MEN1 4735/4885MAPK1 4806/4885
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME DIMT1, FADS2, SCD KMT2A 301/4885MEN1 1276/4885MAPK1 2124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.