SCHEMBL1576779

SCHEMBL1576779

CC(C)COC(=O)C(=CC=C(c1ccccc1)c1ccccc1)C(=O)OCC(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
TSHR P16473 2/20 0.50
RAB9A P51151 2/20 0.43
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
KDM4E B2RXH2 1/20 0.40
HPGD P15428 1/20 0.39
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
P2RX4 Q99571 1/20 0.38
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
MAPT P10636 3/20 0.38
NPC1 O15118 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2446936 0.94 ALDH1A1 (0.45) ALDH1A1TSHRRAB9AKMT2AMEN1
SCHEMBL14156332 0.83 MEN1 (0.60) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL2411929 0.81 CYP19A1 (0.36) TSHRKMT2AMEN1HPGDNPC1
SCHEMBL14018891 0.80 MEN1 (0.33) ALDH1A1TSHRKMT2AMEN1ADRB2
SCHEMBL7162160 0.79 ALDH1A1 (0.60) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL14017683 0.79 KMT2A (0.41) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL14135780 0.79 MEN1 (0.55) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL1576936 0.79 KMT2A (0.41) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL2215501 0.78 MEN1 (0.67) ALDH1A1TSHRKMT2AMEN1KDM4E
SCHEMBL20702134 0.77 ALDH1A1 (0.55) ALDH1A1TSHRRAB9AHPGDADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022138482-A1 POLYMER-CONTAINING O/W-TYPE EMULSION COMPOSITION 住友精化株式会社 2022-06-30 WO disclosed
WO-2022138481-A1 POLYMER-CONTAINING O/W EMULSION COMPOSITION 住友精化株式会社 2022-06-30 WO disclosed
WO-2022138480-A1 O/W TYPE EMULSION COMPOSITION CONTAINING POLYMER 住友精化株式会社 2022-06-30 WO disclosed
EP-2683351-B1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME OREAL (FR) 2019-10-16 EP disclosed
EP-2266531-B1 Cosmetic composition comprising a superabsorbent polymer and an organic UV filter L'ORÉAL (FR) 2017-06-14 EP disclosed
EP-2538914-B1 COSMETIC COMPOSITION COMPRISING A SUPERABSORBENT POLYMER AND AT LEAST A GEMINI SURFACTANT ORÉAL L (FR) 2016-06-15 EP disclosed
US-9364690-B2 Composition comprising a superabsorbent polymer and a gemini surfactant L'OREAL (FR) 2016-06-14 US disclosed
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME OREAL (FR) 2016-03-10 US disclosed
US-20150224046-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT L'OREAL (FR) 2015-08-13 US disclosed
EP-2482793-B1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT ORÉAL L (FR) 2015-04-22 EP disclosed
US-20120269746-A1 USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'OREAL (FR) 2012-10-25 US disclosed
WO-2012119861-A2 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME L'OREAL (FR) 2012-09-13 WO disclosed
EP-2482793-A1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'Oréal (FR) 2012-08-08 EP disclosed
EP-2482791-A1 USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'Oréal (FR) 2012-08-08 EP disclosed
WO-2011038778-A1 USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'OREAL (FR) 2011-04-07 WO disclosed
WO-2011038776-A1 USE OF PIPERIDINE ESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT L'OREAL (FR) 2011-04-07 WO disclosed
US-20100330018-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT L'OREAL (FR) 2010-12-30 US disclosed
EP-2266531-A1 Cosmetic composition comprising a superabsorbent polymer and an organic UV filter L'Oréal (FR) 2010-12-29 EP disclosed
US-20100143276-A1 Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions L'OREAL (FR) 2010-06-10 US disclosed
EP-2193783-A1 Use of an ester derived from 4-carboxy-2-pyrrolidinone as a solvent in cosmetic compositions; cosmetic compositions containing same L'Oreal (FR) 2010-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150224046-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT KRT18, FABP2, FABP4 ALDH1A1 699/4885TSHR 4652/4885RAB9A 3619/4885
US-20160067160-A1 USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME DIMT1, FADS2, SCD ALDH1A1 390/4885TSHR 4271/4885RAB9A 4643/4885
US-20100330018-A1 COMPOSITION CONTAINING A SUPERABSORBENT POLYMER AND AN ORGANIC UV SCREENING AGENT KRT18, FABP2, FABP4 ALDH1A1 699/4885TSHR 4652/4885RAB9A 3619/4885
US-20120269746-A1 USE OF CAPROLACTAM DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS COMPRISING IT DEGS1, CAPN1, PPT1 ALDH1A1 237/4885TSHR 3817/4885RAB9A 3285/4885
US-20100143276-A1 Ester solvents derived from 4-carboxy-2-pyrrolidinone formulated into UV-screening cosmetic compositions FASN, ALOX12, PAH ALDH1A1 201/4885TSHR 3189/4885RAB9A 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.