Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM1A | O60341 | 10/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775278 | 0.79 | MAPT (0.64) | MEN1KMT2AMAPTLMNAKDM1A | |
| SCHEMBL24980301 | 0.74 | KDM1A (0.57) | MEN1KMT2AMAPTLMNAKDM1A | |
| SCHEMBL208025 | 0.71 | PIM1 (0.79) | MEN1KMT2AMAPTLMNAKDM1A | |
| SCHEMBL24495341 | 0.71 | KDM1A (0.51) | MEN1KMT2ALMNAKDM1ASNCA | |
| SCHEMBL29713602 | 0.71 | KDM1A (0.51) | MEN1KMT2ALMNAKDM1ASNCA | |
| SCHEMBL3696468 | 0.70 | SIGMAR1 (0.63) | MEN1KMT2AMAPTLMNAKDM1A | |
| SCHEMBL10052731 | 0.70 | KDM1A (0.64) | MEN1KMT2AMAPTLMNAKDM1A | |
| SCHEMBL10655662 | 0.70 | KMT2A (0.56) | MEN1KMT2AMAPTLMNAKDM1A | |
| SCHEMBL15775236 | 0.70 | MEN1 (0.64) | MEN1KMT2AMAPTLMNAKDM1A | |
| SCHEMBL343282 | 0.70 | KDM1A (0.65) | MEN1KMT2AMAPTLMNAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | disclosed |