Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21467524 | 0.80 | LMNA (0.60) | KDM1AMEN1KMT2ALMNASIGMAR1 | |
| SCHEMBL6866025 | 0.79 | KDM1A (0.55) | KDM1ALMNASIGMAR1PIM1MAPT | |
| SCHEMBL3696468 | 0.78 | SIGMAR1 (0.63) | KDM1AMEN1KMT2ALMNASIGMAR1 | |
| SCHEMBL4231534 | 0.77 | SLC6A2 (0.54) | MEN1KMT2ALMNATDP1DPP7 | |
| SCHEMBL6749822 | 0.76 | KDM1A (0.49) | KDM1ALMNASIGMAR1PIM1MAPT | |
| SCHEMBL15775165 | 0.74 | MEN1 (0.55) | KDM1AMEN1KMT2ALMNASIGMAR1 | |
| SCHEMBL3692906 | 0.73 | HDAC6 (0.59) | KDM1AMEN1KMT2ALMNASIGMAR1 | |
| SCHEMBL30307018 | 0.73 | HDAC6 (0.59) | KDM1AMEN1KMT2ALMNASIGMAR1 | |
| SCHEMBL6866031 | 0.73 | SIGMAR1 (0.52) | KDM1ALMNASIGMAR1PIM1MAPT | |
| SCHEMBL208025 | 0.71 | PIM1 (0.79) | KDM1AMEN1KMT2ALMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007181-A1 | PHENOTHIAZINE ANTIPSYCHOTICS FOR USE IN THE TREATMENT OF GLIOBLASTOMA | VESTLANDETS INNOVASJONSSELSKAP AS (NO) | 2023-02-02 | — | — | WO | disclosed |