Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775131 | 0.82 | PPARG (0.71) | PPARGMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL15775293 | 0.81 | MAPK1 (0.82) | PPARGMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL15775176 | 0.81 | PPARG (0.70) | PPARGMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL15775209 | 0.72 | PPARG (0.47) | PPARGMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL8428762 | 0.71 | MAPT (0.63) | PPARGMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL15775919 | 0.70 | KDM4E (0.64) | PPARGMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL3240026 | 0.70 | MAPT (0.58) | PPARGMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL8428563 | 0.69 | BCHE (0.65) | PPARGMAPK1KDM4EKMT2AMAPT | |
| SCHEMBL10411671 | 0.67 | KMT2A (0.54) | KMT2AMAPTGAAALDH1A1HTT | |
| SCHEMBL8426652 | 0.67 | BCHE (0.67) | PPARGKDM4EKMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | claimed |