Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775129 | 0.83 | PPARG (0.47) | PPARGMAPK1KDM4EMAPTGFER | |
| SCHEMBL15775291 | 0.82 | PPARG (0.52) | PPARGMAPK1KDM4EMAPTGFER | |
| SCHEMBL15775209 | 0.80 | PPARG (0.47) | PPARGMAPK1KDM4EMAPTGFER | |
| SCHEMBL3240026 | 0.76 | MAPT (0.58) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL15775918 | 0.74 | AR (0.46) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL15775176 | 0.74 | PPARG (0.70) | PPARGMAPK1KDM4EMAPTGFER | |
| SCHEMBL8428762 | 0.74 | MAPT (0.63) | PPARGMAPK1KDM4EMAPTMEN1 | |
| SCHEMBL8428563 | 0.71 | BCHE (0.65) | PPARGMAPK1KDM4EMAPTGFER | |
| SCHEMBL9423724 | 0.71 | NOX1 (0.59) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL15775131 | 0.70 | PPARG (0.71) | PPARGMAPK1KDM4EMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014086478-A1 | INHIBITORS OF MALT1 PROTEASE | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-12 | — | — | WO | disclosed |