Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28528748 | 0.82 | ALDH1A1 (0.83) | ALDH1A1NFE2L2HPGDAPOBEC3GKMT2A | |
| SCHEMBL10012898 | 0.81 | POLB (0.58) | ALDH1A1HPGDAPOBEC3GKMT2AMEN1 | |
| SCHEMBL10012896 | 0.81 | POLB (0.58) | ALDH1A1HPGDAPOBEC3GKMT2AMEN1 | |
| SCHEMBL10012630 | 0.74 | POLB (0.49) | ALDH1A1HPGDAPOBEC3GKMT2AMEN1 | |
| SCHEMBL10012633 | 0.74 | POLB (0.49) | ALDH1A1HPGDAPOBEC3GKMT2AMEN1 | |
| SCHEMBL4441637 | 0.74 | ALDH1A1 (0.67) | ALDH1A1HPGDAPOBEC3GKMT2AMEN1 | |
| SCHEMBL4441638 | 0.74 | ALDH1A1 (0.67) | ALDH1A1HPGDAPOBEC3GKMT2AMEN1 | |
| SCHEMBL15780714 | 0.74 | KDM4E (0.55) | ALDH1A1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL9354338 | 0.72 | NFE2L2 (0.67) | ALDH1A1NFE2L2KMT2AMEN1HTT | |
| SCHEMBL9354335 | 0.72 | NFE2L2 (0.67) | ALDH1A1NFE2L2KMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180028478-A1 | ANTIVIRAL COMPOSITIONS DIRECTED AGAINST THE NUCLEOPROTEIN OF INFLUENZA VIRUSES | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2018-02-01 | — | — | US | disclosed |
| US-9783482-B2 | Antiviral compositions directed against the influenza virus nucleoprotein | INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (FR) | 2017-10-10 | — | — | US | disclosed |
| US-20140163107-A1 | ANTIVIRAL COMPOSITIONS DIRECTED AGAINST THE INFLUENZA VIRUS NUCLEOPROTEIN | INSTITUT NATIONAL DE LA RECHERCHE AGRONIMIQUE (FR) | 2014-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180028478-A1 | ANTIVIRAL COMPOSITIONS DIRECTED AGAINST THE NUCLEOPROTEIN OF INFLUENZA VIRUSES | SNRPE, HNRNPA1, ADAR | ALDH1A1 3240/4885NFE2L2 4300/4885HPGD 3463/4885 |
| US-20140163107-A1 | ANTIVIRAL COMPOSITIONS DIRECTED AGAINST THE INFLUENZA VIRUS NUCLEOPROTEIN | SNRPE, HNRNPA1, SNRPF | ALDH1A1 4311/4885NFE2L2 4539/4885HPGD 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.