Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578494 | 0.90 | CA12 (0.43) | POLBATMMEN1KMT2ACTSL | |
| SCHEMBL1578852 | 0.86 | POLB (0.48) | POLBATMCTSLCTSSCTSK | |
| SCHEMBL1578291 | 0.86 | EGFR (0.37) | ATMMEN1KMT2AELANEPRTN3 | |
| SCHEMBL1578391 | 0.85 | KCNA5 (0.49) | CTSLCTSSCTSK | |
| Hydrochloric Acid SCHEMBL1578094 | 0.84 | KCNA5 (0.49) | CTSLCTSSCTSK | |
| SCHEMBL4328756 | 0.78 | CA12 (0.43) | MEN1KMT2AMAPTTSHR | |
| SCHEMBL1335603 | 0.73 | POLB (0.53) | POLBATMCTSLCTSSCTSK | |
| SCHEMBL9782114 | 0.71 | CTRB1 (0.58) | ATMCTSLCTSSCTSKCTRB1 | |
| SCHEMBL9707035 | 0.71 | CTRB1 (0.58) | ATMCTSLCTSSCTSKCTRB1 | |
| SCHEMBL7279121 | 0.71 | CTSL (0.50) | POLBATMCTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310368-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | AstraZeneca AB (SE) | 2011-04-20 | — | — | EP | disclosed |