Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA6 | P23280 | 5/20 | 0.50 |
| ▸ | CA7 | P43166 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA4 | P22748 | 4/20 | 0.50 |
| ▸ | CA5A | P35218 | 4/20 | 0.50 |
| ▸ | CA3 | P07451 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21409765 | 0.80 | CA12 (0.55) | CA12CA6CA7CA9CA14 | |
| SCHEMBL1897721 | 0.76 | — | — | |
| SCHEMBL599056 | 0.76 | CA12 (0.50) | CA12CA6CA7CA9CA14 | |
| SCHEMBL28015356 | 0.76 | CA12 (0.50) | CA12CA6CA7CA9CA14 | |
| SCHEMBL4350835 | 0.74 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| Potassium Ion SCHEMBL4355913 | 0.74 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL8214664 | 0.74 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL27388092 | 0.74 | CA12 (0.48) | CA12CA6CA7CA9CA14 | |
| SCHEMBL10977393 | 0.74 | — | — | |
| SCHEMBL28596714 | 0.73 | CA12 (0.52) | CA12CA6CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220142905-A1 | COSMETIC PRODUCT CONTAINING A MIXTURE OF SILICONES | HENKEL AG & CO. KGAA (DE) | 2022-05-12 | — | — | US | claimed |
| EP-3937890-A1 | COSMETIC AGENT CONTAINING A MIXTURE OF SILICONES | Henkel AG & Co. KGaA (DE) | 2022-01-19 | — | — | EP | claimed |
| WO-2020182475-A1 | COSMETIC AGENT CONTAINING A MIXTURE OF SILICONES | HENKEL AG & CO. KGAA (DE) | 2020-09-17 | — | — | WO | claimed |
| EP-3215227-B1 | OXIDATIVE HAIR DYE COMPOSITION COMPRISING A COMBINATION OF CROSS LINKED AMINATED SILOXANPOLYMERS AND NON IONIC TENSIDS | HENKEL AG & CO KGAA (DE) | 2019-03-13 | — | — | EP | claimed |
| US-10004672-B2 | Oxidation dye including a combination of cross-linked, aminated siloxane polymers and non-ionic surfactants | HENKEL AG & CO. KGAA (DE) | 2018-06-26 | — | — | US | claimed |
| EP-3229920-A1 | HIGH-PERFORMANCE COSMETIC PRODUCTS CONTAINING A POLYORGANOSILOXANE AND A DIPEPTIDE | Evonik Degussa GmbH (DE) | 2017-10-18 | — | — | EP | claimed |
| US-20170231880-A1 | OXIDATION DYE INCLUDING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | HENKEL AG & CO. KGAA (DE) | 2017-08-17 | — | — | US | claimed |
| WO-2016091781-A1 | HIGH-PERFORMANCE COSMETIC PRODUCTS CONTAINING A POLYORGANOSILOXANE AND A DIPEPTIDE | EVONIK DEGUSSA GMBH (DE) | 2016-06-16 | — | — | WO | claimed |
| US-20230374224-A1 | AQUEOUS DISPERSIONS OF AMINO-FUNCTIONALIZED ORGANOPOLYSILOXANES PRE-CROSSLINKED WITH OXALATOPOLYETHERS | WACKER CHEMIE AG (DE) | 2023-11-23 | — | — | US | disclosed |
| WO-2023193903-A1 | AQUEOUS DISPERSIONS OF PRE-CROSSLINKED ORGANOPOLYSILOXANES | WACKER CHEMIE AG (DE) | 2023-10-12 | — | — | WO | disclosed |
| EP-4229116-A1 | AQUEOUS DISPERSIONS OF AMINO-FUNCTIONALIZED ORGANOPOLYSILOXANES PRE-CROSSLINKED WITH OXALATOPOLYETHERS | Wacker Chemie AG (DE) | 2023-08-23 | — | — | EP | disclosed |
| CN-116390990-A | Aqueous dispersions of amino-functional organopolysiloxanes pre-crosslinked with oxalic acid polyethers | 瓦克化学股份公司 | 2023-07-04 | — | — | CN | disclosed |
| EP-3976692-B1 | AQUEOUS DISPERSIONS OF PRE-CROSSLINKED ORGANOPOLYSILOXANES | WACKER CHEMIE AG (DE) | 2023-02-22 | — | — | EP | disclosed |
| US-20220218589-A1 | AQUEOUS DISPERSIONS OF PRE-CROSSLINKED ORGANOPOLYSILOXANES | WACKER CHEMIE AG (DE) | 2022-07-14 | — | — | US | disclosed |
| WO-2007060113-A2 | METHOD FOR PREPARING ?-KETOCARBONYL-FUNCTIONAL ORGANO-SILICIUM COMPOUNDS | WACKER CHEMIE AG (DE) | 2007-05-31 | — | — | WO | disclosed |
| EP-1773920-A1 | METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES | Wacker Chemie AG (DE) | 2007-04-18 | — | — | EP | disclosed |
| US-20060258820-A1 | Process for preparing dispersions of crosslinked organopolysiloxanes | WACKER CHEMIE AG (DE) | 2006-11-16 | — | — | US | disclosed |
| EP-1721926-A1 | Process for the production of dispersions of cross linked organopolysiloxanes | Wacker Chemie AG (DE) | 2006-11-15 | — | — | EP | disclosed |
| WO-2006015740-A1 | METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES | WACKER CHEMIE AG (DE) | 2006-02-16 | — | — | WO | disclosed |
| US-5466746-A | Emulsions of organopolysiloxanes containing polar groups with alkyl polyglycosides as emulsifiers | WACKER-CHEMIE GMBH (DE) | 1995-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004672-B2 | Oxidation dye including a combination of cross-linked, aminated siloxane polymers and non-ionic surfactants | KRT18, PLOD3, SORD | CA12 1746/4885CA6 2798/4885CA7 1458/4885 |
| US-20170231880-A1 | OXIDATION DYE INCLUDING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | KRT18, PLOD3, SORD | CA12 1746/4885CA6 2798/4885CA7 1458/4885 |
| US-20220142905-A1 | COSMETIC PRODUCT CONTAINING A MIXTURE OF SILICONES | SQLE, LIPA, HSD17B4 | CA12 1271/4885CA6 1655/4885CA7 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.