SCHEMBL157883

SCHEMBL157883

COc1ccc(S(=O)(=O)O)c([NH])c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MPL P40238 1/20 0.40
PKM P14618 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
GAA P10253 2/20 0.39
PRKAB2 O43741 1/20 0.39
PRKAG1 P54619 1/20 0.39
PRKAA2 P54646 1/20 0.39
PRKAA1 Q13131 1/20 0.39
PRKAG3 Q9UGI9 1/20 0.39
PRKAG2 Q9UGJ0 1/20 0.39
PRKAB1 Q9Y478 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158763 0.85 L3MBTL1 (0.45) L3MBTL1MPLPKMSMN1; SMN2GAA
SCHEMBL1155621 0.79 NPC1 (0.52) L3MBTL1KDM4EMPLPKMSMN1; SMN2
SCHEMBL1817467 0.79 PKM (0.55) L3MBTL1MPLPKMSMN1; SMN2GAA
SCHEMBL669063 0.79 GAA (0.54) L3MBTL1GAACA1CA2NPC1
SCHEMBL27724224 0.79 KEAP1 (0.47) L3MBTL1MPLPKMSMN1; SMN2GAA
SCHEMBL10745617 0.78 GAA (0.52) L3MBTL1SMN1; SMN2GAACA1CA2
SCHEMBL18700925 0.78 PRKAB2 (0.48) L3MBTL1MPLPKMSMN1; SMN2GAA
SCHEMBL10740495 0.78 GAA (0.52) L3MBTL1SMN1; SMN2GAACA1CA2
SCHEMBL10497795 0.78 SMN1; SMN2 (0.54) L3MBTL1MPLPKMSMN1; SMN2GAA
Hydrochloric Acid SCHEMBL2532256 0.78 GAA (0.52) L3MBTL1GAACA1CA2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120056931-A1 MAGENTA COLORING MATTER, INK COMPOSITION, AND COLORED BODY NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-03-08 US disclosed
US-5136028-A Red; colorfastness CIBA-GEIGY CORPORATION (US) 1992-08-04 US disclosed
EP-0428482-A1 Reactive dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1991-05-22 EP disclosed