SCHEMBL158017

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11874262	0.81	HTR6 (0.55)	SLC6A4KDM4ELMNAPOLBHTR1A
	SCHEMBL7255363	0.76	HTR6 (0.58)	SLC6A4KDM4ELMNAPOLBHTR1A
	Bromide SCHEMBL9325716	0.75	HTR6 (0.57)	SLC6A4KDM4ELMNAPOLBHTR1A
	SCHEMBL5008976	0.71	SLC6A4 (0.68)	SLC6A4KDM4ELMNAPOLBHTR1A
	SCHEMBL6594982	0.71	HTR2C (0.47)	KDM4EALOX15HSD17B10DRD2QDPR
	Bromide SCHEMBL7870845	0.70	HTR6 (0.42)	SLC6A4KDM4ELMNAPOLBHTR1A
	SCHEMBL1078756	0.70	KDM4E (0.55)	SLC6A4KDM4ELMNAPOLBHTR1A
	SCHEMBL29387382	0.70	KDM4E (0.55)	SLC6A4KDM4ELMNAPOLBHTR1A
	Hydrochloric Acid SCHEMBL2263936	0.70	KDM4E (0.55)	SLC6A4KDM4ELMNAPOLBHTR1A
	SCHEMBL5153625	0.70	ADRA2A (0.56)	SLC6A4KDM4ELMNAHTR1ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.