SCHEMBL5175967

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24512757	0.88	TDP1 (0.44)	SOS1MAOAMAOBTDP1AR
	SCHEMBL31556425	0.86	LMNA (0.50)	SOS1MAOAMAOBERN1FFAR4
	SCHEMBL2536648	0.86	LMNA (0.50)	SOS1MAOAMAOBERN1FFAR4
	SCHEMBL15809138	0.80	TDP1 (0.62)	SOS1MAOAMAOBTDP1ERN1
	SCHEMBL11288471	0.79	FFAR4 (0.43)	MAOAMAOBERN1FFAR4NFE2L2
	SCHEMBL27720125	0.79	HSPB1 (0.58)	ERN1POLBMEN1KMT2ANPSR1
	SCHEMBL29958016	0.78	ERN1 (0.59)	TDP1ERN1HSD17B10MEN1KMT2A
	SCHEMBL42333	0.78	ERN1 (0.59)	TDP1ERN1HSD17B10MEN1KMT2A
	SCHEMBL18957581	0.77	MAOA (0.46)	MAOAMAOBTDP1ERN1SMN1; SMN2
	SCHEMBL15904234	0.77	ERN1 (0.46)	TDP1ERN1SMN1; SMN2POLBCASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.