SCHEMBL15810282

SCHEMBL15810282

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nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.36
POLB P06746 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17087399 0.79 RAB9A (0.34) RAB9AL3MBTL1
SCHEMBL15810284 0.78 DPP4 (0.42) POLBNPSR1L3MBTL1
SCHEMBL12197946 0.78 POLB (0.53) RAB9APOLBNPSR1L3MBTL1
SCHEMBL15810285 0.75 SMN1; SMN2 (0.34) POLBNPSR1L3MBTL1
SCHEMBL15810294 0.73 ECE1 (0.33) POLBL3MBTL1
SCHEMBL12197867 0.68 RAB9A (0.41) RAB9APOLBNPSR1L3MBTL1
SCHEMBL8418308 0.68 BLM (0.43) RAB9AL3MBTL1
SCHEMBL15808531 0.68 CPN1 (0.40) RAB9A
SCHEMBL17087480 0.67 PAOX (0.37) POLBL3MBTL1
SCHEMBL15810306 0.66 CHRM2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9895412-B2 Cyclic depsipeptide compounds and their uses CYPRALIS LIMITED (GB) 2018-02-20 US disclosed
US-20170007664-A1 CYCLIC DEPSIPEPTIDE COMPOUNDS AND THEIR USES CYPRALIS LIMITED (GB) 2017-01-12 US disclosed
WO-2014091239-A1 NOVEL PHARMACEUTICAL FORMULATIONS AND THEIR USE IN THE TREATMENT OF PERIODONTAL DISEASE PERIOC LTD (GB) 2014-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170007664-A1 CYCLIC DEPSIPEPTIDE COMPOUNDS AND THEIR USES FKBP14, FKBP1A, PIN1 RAB9A 3026/4885POLB 3674/4885NPSR1 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.