Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | MMP3 | P08254 | 3/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.51 |
| ▸ | HRH2 | P25021 | 5/20 | 0.51 |
| ▸ | HRH1 | P35367 | 5/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17231860 | 0.95 | CYP11B1 (0.53) | HDAC1HDAC2MMP3CYP11B1CYP11B2 | |
| SCHEMBL20275451 | 0.87 | HDAC1 (0.51) | HDAC1HDAC2MMP3CYP11B1CYP11B2 | |
| SCHEMBL18079151 | 0.87 | HDAC1 (0.67) | HDAC1HDAC2MMP3HRH3HRH2 | |
| SCHEMBL29444063 | 0.87 | HDAC1 (0.67) | HDAC1HDAC2MMP3HRH3HRH2 | |
| SCHEMBL16841044 | 0.87 | HDAC1 (0.67) | HDAC1HDAC2MMP3HRH3HRH2 | |
| SCHEMBL26602050 | 0.85 | MMP3 (0.66) | HDAC1HDAC2MMP3HRH3HRH2 | |
| SCHEMBL16615579 | 0.85 | TSHR (0.49) | HDAC1HDAC2MMP3CYP11B1CYP11B2 | |
| SCHEMBL7048536 | 0.82 | MMP3 (0.79) | HDAC1HDAC2MMP3MMP2MMP1 | |
| SCHEMBL1777722 | 0.81 | KCNA3 (0.64) | HDAC1HDAC2MMP3HRH3HRH2 | |
| SCHEMBL5526919 | 0.81 | HRH3 (0.66) | HDAC1HDAC2MMP3HRH3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711196-B2 | Bimesogenic compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2020-07-14 | — | — | US | disclosed |
| US-10343982-B2 | Compounds and mesogenic media | MERCK PATENT GMBH (DE) | 2019-07-09 | — | — | US | disclosed |
| EP-3049506-B1 | COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-06-14 | — | — | EP | disclosed |
| EP-2928985-B1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| US-20160229795-A1 | COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20160229795-A1 | COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | US | disclosed |
| US-20150315470-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150315470-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| WO-2015043713-A1 | COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2015-04-02 | — | — | WO | disclosed |
| WO-2014090372-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2014-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160229795-A1 | COMPOUNDS AND MESOGENIC MEDIA | MTX1, NEFM, MTX2 | HDAC1 4134/4885HDAC2 4827/4885MMP3 256/4885 |
| US-10343982-B2 | Compounds and mesogenic media | MTX1, NEFM, MTX2 | HDAC1 4134/4885HDAC2 4827/4885MMP3 256/4885 |
| US-20150315470-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | SP1, FOXM1, S100A11 | HDAC1 2242/4885HDAC2 3725/4885MMP3 288/4885 |
| US-10711196-B2 | Bimesogenic compounds and mesogenic media | BMP2, NEFM, MTX1 | HDAC1 4587/4885HDAC2 4840/4885MMP3 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.