SCHEMBL158113

SCHEMBL158113

CCCc1nc2cc(C(=O)O)cc(C)c2[nH]1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.41
ALDH1A1 P00352 1/20 0.40
MAPK1 P28482 1/20 0.40
KDM4E B2RXH2 3/20 0.37
ADORA1 P30542 3/20 0.37
ADORA3 P0DMS8 2/20 0.37
ADORA2A P29274 2/20 0.37
KMT2A Q03164 2/20 0.37
RECQL P46063 2/20 0.37
KDM5A P29375 1/20 0.37
KDM5B Q9UGL1 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 3/20 0.36
HSP90AA1 P07900 1/20 0.36
ESR2 Q92731 1/20 0.36
KDM4C Q9H3R0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4437776 0.97 ALDH1A1 (0.41) APEX1ALDH1A1MAPK1KDM4EADORA1
SCHEMBL8847760 0.88 ADORA1 (0.46) APEX1ALDH1A1MAPK1KDM4EADORA1
SCHEMBL3707021 0.85 CA12 (0.42) ALDH1A1MAPK1KDM4EKMT2AHRH3
SCHEMBL1918976 0.85 MAPT (0.40) ALDH1A1MAPK1KDM4EKMT2AMEN1
SCHEMBL1918064 0.81 F9 (0.36) KDM4EADORA1KMT2ARECQL
SCHEMBL5027701 0.80 ADORA1 (0.35) MAPK1KDM4EADORA1ADORA3ADORA2A
SCHEMBL1919439 0.79 ALDH1A1 (0.36) ALDH1A1MAPK1RAB9A
SCHEMBL13907870 0.79 KMT2A (0.40) ALDH1A1KDM4EADORA1ADORA3ADORA2A
SCHEMBL13907803 0.79 TDP1 (0.53) ALDH1A1KDM4EKMT2AHRH3MEN1
SCHEMBL1917751 0.77 ALDH1A1 (0.44) ALDH1A1KDM4EKMT2ARECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040354-A Telmisartan intermediate intermediate and preparation method thereof 复星万邦(江苏)医药集团有限公司 2025-05-27 CN claimed
CN-117276497-A Asphalt-based coated resin-based hard carbon composite material and preparation method and application thereof 常州烯源谷新材料科技有限公司 2023-12-22 CN claimed
CN-114573513-B Synthesis method of telmisartan intermediate 济南大学 2023-05-16 CN claimed
CN-114573513-A Synthesis method of telmisartan intermediate 济南大学 2022-06-03 CN claimed
CN-112251770-B Novel electrochemical preparation method of antihypertensive drug telmisartan intermediate 湖南大学 2021-07-27 CN claimed
CN-112251770-A Novel electrochemical preparation method of antihypertensive drug telmisartan intermediate 湖南大学 2021-01-22 CN claimed
CN-109320461-B Preparation method of telmisartan intermediate 迪嘉药业集团有限公司 2020-02-07 CN claimed
CN-110698410-A Preparation method of 2-n-propyl-4-methyl-6- (1' -methylbenzimidazole-2-yl) benzimidazole 合肥立方制药股份有限公司 2020-01-17 CN claimed
CN-107118161-B Synthesis method of 2-n-propyl-4-methylbenzimidazole-6-carboxylic acid 湖北工业大学 2019-12-31 CN claimed
CN-109320461-A A kind of preparation method of telmisartan intermediate 威海迪素制药有限公司 2019-02-12 CN claimed
CN-102659686-B Preparation method of 2-n-propyl-4-methyl-6-(1'-methylbenzimidazolyl-2-yl)benzimidazole NINGBO CHEMGOO PHARMACEUTICAL TECHNOLOGY INNOVATION LTD 2014-11-26 CN claimed
CN-103755641-A Synthetic method for telmisartan intermediate WEIHAI DIZHIYA PHARMACHEM DEV CO LTD 2014-04-30 CN claimed
CN-102659686-A Preparation method of 2-n-propyl-4-methyl-6-(1'-methylbenzimidazolyl-2-yl)benzimidazole NINGBO CHEMGOO PHARMA TECH CO LTD 2012-09-12 CN claimed
US-7943781-B2 Process for preparing telmisartan DR. REDDY'S LABORATORIES LIMITED (IN) 2011-05-17 US claimed
WO-2010081670-A2 PROCESS FOR THE PREPARATION OF BENZIMIDAZOLES LONZA LTD (CH) 2010-07-22 WO claimed
CN-101172968-B 2-propyl-4 methyl-6-(tolimidazole-2group) benzoglioxaline salt and method for producing the same ZHEJIANG TIANYU PHARMACEUTICAL CO LTD 2010-05-12 CN claimed
EP-1805146-A4 PROCESS FOR PREPARING TELMISARTAN REDDYS LAB LTD DR (IN) 2009-01-14 EP claimed
US-20070287840-A1 Process for Preparing Telmisartan DR. REDDY'S LABORATORIES LIMITED (IN) 2007-12-13 US claimed
EP-1805146-A2 PROCESS FOR PREPARING TELMISARTAN Dr. Reddy's Laboratories Ltd. (IN) 2007-07-11 EP claimed
WO-2006044754-A2 PROCESS FOR PREPARING TELMISARTAN DR. REDDY'S LABORATORIES LTD. (IN) 2006-04-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070287840-A1 Process for Preparing Telmisartan AGT, TTR, REN APEX1 1851/4885ALDH1A1 2741/4885MAPK1 1129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.