Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158113 | 0.80 | APEX1 (0.41) | ADORA1KDM4EADORA3ADORA2AKMT2A | |
| SCHEMBL1118704 | 0.79 | ACACB (0.39) | KDM4EKMT2AMAPTTP53MAPK1 | |
| SCHEMBL9754854 | 0.77 | KDM4E (0.45) | KDM4EKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4437776 | 0.77 | ALDH1A1 (0.41) | ADORA1KDM4EADORA3ADORA2AKMT2A | |
| SCHEMBL3707021 | 0.76 | CA12 (0.42) | KDM4EKMT2AMAPTMAPK1 | |
| SCHEMBL1918976 | 0.76 | MAPT (0.40) | KDM4EKMT2AMAPTMAPK1 | |
| SCHEMBL13907870 | 0.75 | KMT2A (0.40) | ADORA1KDM4EADORA3ADORA2AKMT2A | |
| SCHEMBL1918152 | 0.73 | ADORA1 (0.38) | ADORA1KDM4EADORA3ADORA2AKMT2A | |
| SCHEMBL3712699 | 0.72 | KMT2A (0.38) | ADORA1KDM4EADORA3ADORA2AKMT2A | |
| SCHEMBL25110136 | 0.72 | ADORA1 (0.37) | ADORA1KDM4EADORA3ADORA2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912951-A1 | PREPARATION OF 1,7` -DIMETHYL-2 `-PROPYL-2,5` -BI-1H-BENZIMIDAZOLE | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007009967-A1 | PREPARATION OF 1,7′-DIMETHYL-2′-PROPYL-2,5′-BI-1H-BENZIMIDAZOLE | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-01-25 | — | — | WO | disclosed |