Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707021 | 0.90 | CA12 (0.42) | MAPTPKMKDM4EKMT2AMEN1 | |
| SCHEMBL158113 | 0.85 | APEX1 (0.41) | KDM4EKMT2AMEN1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4437776 | 0.83 | ALDH1A1 (0.41) | KDM4EKMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL1917751 | 0.81 | ALDH1A1 (0.44) | MAPTGAAKDM4EKMT2AMEN1 | |
| SCHEMBL6170453 | 0.80 | KDM4E (0.45) | MAPTGAAKDM4EPPARAKMT2A | |
| SCHEMBL1918064 | 0.80 | F9 (0.36) | MAPTKDM4EKMT2ASMN1; SMN2HTT | |
| SCHEMBL159894 | 0.79 | ACACB (0.43) | MAPTGAAPKMKDM4EPPARG | |
| SCHEMBL1919439 | 0.78 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MAPK1RAB9A | |
| Hydrochloric Acid SCHEMBL14775596 | 0.78 | ACACB (0.42) | MAPTGAAPKMKDM4EPPARG | |
| SCHEMBL8906504 | 0.77 | L3MBTL1 (0.54) | MAPTGAAPKMKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572243-B | Green preparation method of telmisartan key intermediate | 湖南大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-115572243-A | Green preparation method of telmisartan key intermediate | 湖南大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-112251770-B | Novel electrochemical preparation method of antihypertensive drug telmisartan intermediate | 湖南大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-111041516-B | New preparation method of telmisartan intermediate of antihypertensive drug | 湖南大学 | 2021-06-25 | — | — | CN | disclosed |
| CN-112251770-A | Novel electrochemical preparation method of antihypertensive drug telmisartan intermediate | 湖南大学 | 2021-01-22 | — | — | CN | disclosed |
| CN-111041516-A | New preparation method of telmisartan intermediate of antihypertensive drug | 湖南大学 | 2020-04-21 | — | — | CN | disclosed |
| EP-3081213-B1 | TRICYCLIC COMPOUND | KYOWA KIRIN CO LTD (JP) | 2020-04-01 | — | — | EP | disclosed |
| US-9475805-B2 | Tricyclic compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2016-10-25 | — | — | US | disclosed |
| EP-3081213-A1 | TRICYCLIC COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2016-10-19 | — | — | EP | disclosed |
| US-20150291587-A1 | TRICYCLIC COMPOUND | KYOWA KIRIN CO., LTD. (JP) | 2015-10-15 | — | — | US | disclosed |
| US-8242151-B2 | Tricyclic compounds | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20110201640-A1 | TRICYCLIC COMPOUND | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2327690-A1 | TRICYCLIC COMPOUND | Kyowa Hakko Kirin Co., Ltd. (JP) | 2011-06-01 | — | — | EP | disclosed |
| CN-101921235-A | Preparation method of telmisartan | YICHANG CHANGJIANG PHARMACEUTICAL CO LTD | 2010-12-22 | — | — | CN | disclosed |
| WO-2010081670-A2 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLES | LONZA LTD (CH) | 2010-07-22 | — | — | WO | disclosed |
| US-20090176760-A1 | TRICYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-1988091-A1 | TRICYCLIC COMPOUNDS | Kyowa Hakko Kogyo Co., Ltd (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-7012151-B1 | Method for nitrating aniline derivatives | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2006-03-14 | — | — | US | disclosed |
| EP-1173407-A1 | METHOD FOR NITRATING ANILINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GmbH (DE) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000063158-A1 | METHOD FOR NITRATING ANILINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291587-A1 | TRICYCLIC COMPOUND | PPARA, PPARG, PPARD | MAPT 4669/4885GAA 2399/4885PKM 1770/4885 |
| US-20110201640-A1 | TRICYCLIC COMPOUND | PPARG, PPARA, PPARD | MAPT 4554/4885GAA 2804/4885PKM 1903/4885 |
| US-20090176760-A1 | TRICYCLIC COMPOUNDS | PPARG, PPARD, PPARA | MAPT 4588/4885GAA 3391/4885PKM 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.