Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387438 | 0.88 | DRD2 (0.50) | MEN1KMT2AEPHX2KDM4EDRD2 | |
| SCHEMBL1581501 | 0.88 | DRD2 (0.45) | MEN1KMT2AAPPCYP3A4CYP2C9 | |
| SCHEMBL1581499 | 0.85 | MEN1 (0.58) | MEN1KMT2AKDM4EDRD2OPRM1 | |
| SCHEMBL5075026 | 0.81 | DRD2 (0.44) | MEN1KMT2AEPHX2KDM4EDRD2 | |
| SCHEMBL2229509 | 0.81 | MEN1 (0.62) | MEN1KMT2AKDM4EDRD2OPRM1 | |
| SCHEMBL1824469 | 0.80 | DRD2 (0.46) | MEN1KMT2AEPHX2DRD2OPRM1 | |
| SCHEMBL1581749 | 0.80 | OPRM1 (0.51) | MEN1KMT2ADRD2OPRM1OPRD1 | |
| SCHEMBL1581427 | 0.80 | OPRM1 (0.51) | CYP3A4DRD2OPRM1OPRD1OPRK1 | |
| SCHEMBL5375143 | 0.79 | KDM4E (0.43) | MEN1KMT2AEPHX2KDM4EDRD2 | |
| SCHEMBL5381232 | 0.79 | CCR1 (0.50) | MEN1KMT2AAPPCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720872-B1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2011-04-20 | — | — | EP | disclosed |