Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371705 | 0.95 | OPRM1 (0.55) | OPRM1OPRK1OPRL1OPRD1CYP46A1 | |
| SCHEMBL1581499 | 0.84 | MEN1 (0.58) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL1581427 | 0.84 | OPRM1 (0.51) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL1581919 | 0.84 | OPRM1 (0.56) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 | |
| SCHEMBL1581880 | 0.81 | OPRL1 (0.50) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL1581964 | 0.80 | KMT2A (0.52) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL795975 | 0.80 | ALDH1A1 (0.56) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL1581993 | 0.80 | MEN1 (0.44) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL1581807 | 0.79 | OPRL1 (0.58) | OPRM1OPRK1OPRL1OPRD1DRD2 | |
| SCHEMBL4725181 | 0.79 | OPRM1 (0.55) | OPRM1OPRK1OPRL1OPRD1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720872-B1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2011-04-20 | — | — | EP | disclosed |