Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | CCR1 | P32246 | 5/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229509 | 0.95 | MEN1 (0.62) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL23365138 | 0.89 | MEN1 (0.60) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL4622767 | 0.86 | KMT2A (0.56) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL1581993 | 0.85 | MEN1 (0.44) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL1581501 | 0.85 | DRD2 (0.45) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL1581749 | 0.84 | OPRM1 (0.51) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL1581427 | 0.84 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1CCR1 | |
| SCHEMBL8164463 | 0.83 | CA12 (0.66) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13923623 | 0.81 | MEN1 (0.61) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL1581919 | 0.81 | OPRM1 (0.56) | MEN1KMT2AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720872-B1 | ARYL AND HETEROARYL-PIPERIDINECARBOXYLATE DERIVATIVES, THE PREPARATION AND THE USE THEREOF IN THE FORM OF FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2011-04-20 | — | — | EP | disclosed |