Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6070145 | 0.81 | L3MBTL1 (0.55) | ALDH1A1SMN1; SMN2MAPTKMT2AL3MBTL1 | |
| SCHEMBL27734467 | 0.79 | L3MBTL1 (0.46) | ALDH1A1SMN1; SMN2USP2KMT2AL3MBTL1 | |
| SCHEMBL15052377 | 0.74 | GAA (0.79) | ALDH1A1SMN1; SMN2MAPTGAAUSP2 | |
| SCHEMBL1101965 | 0.74 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MAPTGAAUSP2 | |
| SCHEMBL1791418 | 0.73 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2GAAUSP2KMT2A | |
| SCHEMBL6069944 | 0.72 | CA2 (0.50) | ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL2687430 | 0.72 | GSK3B (0.40) | ALDH1A1SMN1; SMN2MAPTGAAUSP2 | |
| SCHEMBL28078917 | 0.72 | TRPV4 (0.47) | ALDH1A1SMN1; SMN2MAPTGAAUSP2 | |
| SCHEMBL3568679 | 0.72 | POLB (0.68) | SMN1; SMN2USP2KMT2AL3MBTL1TSHR | |
| SCHEMBL10568810 | 0.71 | MAPT (0.62) | ALDH1A1SMN1; SMN2MAPTGAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935260-A1 | BET-PROTEIN-INHIBITING DIHYDROPYRIDOPYRAZINONES | Bayer Pharma Aktiengesellschaft (DE) | 2015-10-28 | — | — | EP | claimed |
| WO-2014095774-A1 | BET-PROTEIN-INHIBITING DIHYDROPYRIDOPYRAZINONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-06-26 | — | — | WO | claimed |