SCHEMBL15823936

SCHEMBL15823936

Cc1cc(C)c(C(=O)P(=O)(Sc2ccccc2)C(=O)c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
KCNH2 Q12809 1/20 0.37
MMP1 P03956 1/20 0.36
MMP9 P14780 1/20 0.36
MMP13 P45452 1/20 0.36
ADAM17 P78536 1/20 0.36
MAPK1 P28482 1/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 3/20 0.35
CRHR1 P34998 1/20 0.34
ACP3 P15309 1/20 0.34
RAB9A P51151 2/20 0.34
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
TAS1R2 Q8TE23 2/20 0.33
METAP2 P50579 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7187900 0.78 MAPT (0.36) LMNAMMP1MMP9MMP13ADAM17
SCHEMBL20457644 0.75 TAS1R3 (0.39) LMNAMAPK1KMT2AMEN1HPGD
Biphenyl SCHEMBL28338390 0.75 SMN1; SMN2 (0.44) LMNAKMT2AMEN1HPGDSMN1; SMN2
SCHEMBL27967065 0.75 LMNA (0.43) LMNAKMT2AMEN1HPGDSMN1; SMN2
SCHEMBL15158 0.75 LMNA (0.40) LMNAKMT2AMEN1HPGDSMN1; SMN2
SCHEMBL27651 0.75 LMNA (0.43) LMNAKMT2AMEN1HPGDSMN1; SMN2
SCHEMBL8398564 0.74 NR1I2 (0.48) LMNAMMP1MMP9MMP13ADAM17
SCHEMBL25250816 0.73 LMNA (0.39) LMNAKMT2AMEN1HPGDSMN1; SMN2
SCHEMBL117062 0.73 CFTR (0.41) LMNAKMT2AMEN1HPGDSMN1; SMN2
Water SCHEMBL21269928 0.73 LMNA (0.42) LMNAKMT2AMEN1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181249-A Derivatives of bisacylphosphinic acids, their preparation and their use as photoinitiators IGM集团公司 2022-03-15 CN disclosed
CN-110845530-A Derivatives of bisacylphosphinic acids, their preparation and their use as photoinitiators IGM集团公司 2020-02-28 CN disclosed
EP-2935289-B1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B V (NL) 2019-06-26 EP disclosed
EP-2935289-B1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B V (NL) 2019-06-26 EP disclosed
EP-3459957-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM Group B.V. (NL) 2019-03-27 EP disclosed
EP-3459957-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM Group B.V. (NL) 2019-03-27 EP disclosed
US-10040810-B2 Derivatives of bisacylphosphinic acid, their preparation and use as photoinitiators BASF SE (DE) 2018-08-07 US disclosed
US-10040810-B2 Derivatives of bisacylphosphinic acid, their preparation and use as photoinitiators BASF SE (DE) 2018-08-07 US disclosed
US-10040810-B2 Derivatives of bisacylphosphinic acid, their preparation and use as photoinitiators BASF SE (DE) 2018-08-07 US disclosed
US-20160039851-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B.V. (NL) 2016-02-11 US disclosed
US-20160039851-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B.V. (NL) 2016-02-11 US disclosed
US-20160039851-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS IGM GROUP B.V. (NL) 2016-02-11 US disclosed
EP-2935289-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS BASF SE (DE) 2015-10-28 EP disclosed
WO-2014095724-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS BASF SE (DE) 2014-06-26 WO disclosed
WO-2014095724-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS BASF SE (DE) 2014-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160039851-A1 DERIVATIVES OF BISACYLPHOSPHINIC ACID, THEIR PREPARATION AND USE AS PHOTOINITIATORS ARSA, ACSL6, RER1 LMNA 2717/4885KCNH2 831/4885MMP1 4778/4885
US-10040810-B2 Derivatives of bisacylphosphinic acid, their preparation and use as photoinitiators ARSA, RER1, ACSL6 LMNA 2186/4885KCNH2 582/4885MMP1 4798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.