Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 6/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.46 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.43 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.43 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | POLG | P54098 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16144364 | 0.92 | IMPDH2 (0.43) | IMPDH2IMPDH1FUT5TAS1R3TAS1R1 | |
| SCHEMBL15828230 | 0.90 | TGM2 (0.55) | FUT5TGM2P2RY6POLGKRAS | |
| SCHEMBL15828308 | 0.90 | TGM2 (0.55) | FUT5TGM2P2RY6POLGKRAS | |
| SCHEMBL16144271 | 0.89 | POLG (0.42) | IMPDH2IMPDH1FUT5TAS1R3TAS1R1 | |
| SCHEMBL16367979 | 0.89 | IMPDH2 (0.46) | IMPDH2IMPDH1FUT5TAS1R3TAS1R1 | |
| SCHEMBL15837321 | 0.85 | POLG (0.42) | IMPDH2IMPDH1TAS1R3TAS1R1TGM2 | |
| SCHEMBL15837297 | 0.85 | POLG (0.42) | IMPDH2IMPDH1TAS1R3TAS1R1TGM2 | |
| SCHEMBL16368022 | 0.85 | POLRMT (0.47) | IMPDH2IMPDH1FUT5TAS1R3TAS1R1 | |
| SCHEMBL15070388 | 0.84 | IMPDH2 (0.45) | IMPDH2IMPDH1FUT5TAS1R3TAS1R1 | |
| SCHEMBL20693191 | 0.83 | FUT5 (0.54) | FUT5TAS1R3TAS1R1P2RX3TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9211300-B2 | 4′-fluoro nucleosides for the treatment of HCV | IDENIX PHARMACEUTICALS LLC (US) | 2015-12-15 | — | — | US | disclosed |
| US-20140178338-A1 | 4'-FLUORO NUCLOSIDES FOR THE TREATMENT OF HCV | UNIVERSITE DE MONTPELLIER (FR) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140178338-A1 | 4'-FLUORO NUCLOSIDES FOR THE TREATMENT OF HCV | FBL, HNRNPLL, SLC28A1 | IMPDH2 2301/4885IMPDH1 1422/4885FUT5 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.