SCHEMBL15828656

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23956117	0.87	HTR2C (0.60)	HTR2CHTR2AHTR1DHTR6NOS3
	SCHEMBL14093224	0.81	KCNH2 (0.47)	HTR1DHTR6KCNH2
	SCHEMBL16939364	0.80	HTR2C (0.63)	HTR2CHTR2AHTR1DHTR6NOS3
	SCHEMBL13637248	0.79	KCNH2 (0.50)	HTR2CHTR2AKCNH2KDM4E
	SCHEMBL13483885	0.79	GLO1 (0.46)	HTR2CHTR2AHTR6KCNH2
	SCHEMBL22742674	0.78	HTR6 (0.56)	HTR2CHTR2AHTR1DHTR6NOS3
	SCHEMBL20540198	0.78	HTR2C (0.61)	HTR2CHTR2AHTR1DHTR6NOS3
	SCHEMBL6597437	0.78	HTR2C (0.61)	HTR2CHTR2AHTR1DHTR6NOS3
	SCHEMBL23956081	0.78	HTR2A (0.69)	HTR2CHTR2AHTR1DHTR6NOS3
	SCHEMBL14016155	0.78	HTR2C (0.61)	HTR2CHTR2AHTR1DHTR6NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.