SCHEMBL15828665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15646394	0.84	CDC7 (0.44)	CDC7PIM1CDK9IKBKBCHUK
	SCHEMBL15646135	0.82	CDC7 (0.47)	CDC7PIM1CDK9IKBKBCHUK
	SCHEMBL13507207	0.77	IKBKB (0.46)	CDK9IKBKBCHUKCLK4CLK2
	SCHEMBL3413744	0.76	IKBKB (0.45)	CDC7PIM1CDK9IKBKBCHUK
	SCHEMBL31420487	0.76	IKBKB (0.45)	CDC7PIM1CDK9IKBKBCHUK
	SCHEMBL1431235	0.76	IKBKB (0.45)	IKBKBCHUKALDH1A1
	SCHEMBL15652185	0.75	IKBKB (0.45)	IKBKBCHUKALDH1A1KDM4E
	SCHEMBL2215486	0.73	IKBKB (0.46)	IKBKBCHUKAAK1
	SCHEMBL24843391	0.72	CDC7 (0.44)	CDC7PIM1CDK9IKBKBCHUK
	SCHEMBL16897070	0.72	PIM1 (0.47)	CDC7PIM1CDK9ROCK2ROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.