Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PRKDC | P78527 | 9/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15829531 | 0.84 | MAPT (0.47) | PARP1PRKDCMTORSMN1; SMN2RAB9A | |
| SCHEMBL15829525 | 0.82 | PARP1 (0.47) | PARP1PRKDCMTORSMN1; SMN2RAB9A | |
| SCHEMBL19794409 | 0.80 | HSD17B10 (0.38) | PARP1PRKDCMTORSMN1; SMN2RAB9A | |
| SCHEMBL1369733 | 0.79 | KDM4E (0.46) | PARP1PRKDCMTORSMN1; SMN2RAB9A | |
| SCHEMBL15829532 | 0.78 | PARP1 (0.41) | PARP1PRKDCMTORSMN1; SMN2RAB9A | |
| SCHEMBL15829300 | 0.77 | PRKDC (0.42) | PARP1PRKDCMTORSMN1; SMN2RAB9A | |
| SCHEMBL15829297 | 0.76 | PRKDC (0.44) | PARP1PRKDCMTORSMN1; SMN2RAB9A | |
| SCHEMBL18015485 | 0.75 | PRMT5 (0.39) | PARP1PRKDCMTORTP53 | |
| SCHEMBL15829527 | 0.75 | KDM4E (0.44) | SMN1; SMN2RAB9AMAPTTP53MAPK1 | |
| SCHEMBL15829529 | 0.74 | MAPT (0.44) | PARP1PRKDCMTORSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| WO-2020212296-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-10-22 | — | — | WO | disclosed |
| EP-2935293-B1 | IRIDIUM COMPLEXES AND THEIR USE IN ELECTRONIC DEVICES, ESPECIALLY ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-08-21 | — | — | EP | disclosed |
| EP-2935293-B1 | IRIDIUM COMPLEXES AND THEIR USE IN ELECTRONIC DEVICES, ESPECIALLY ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-08-21 | — | — | EP | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| EP-3328872-B1 | ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-05-29 | — | — | EP | disclosed |
| US-20180226591-A1 | ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180226591-A1 | ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| WO-2017016634-A1 | ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-02-02 | — | — | WO | disclosed |
| WO-2016124304-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-08-11 | — | — | WO | disclosed |
| US-20150318498-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150318498-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150318498-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| WO-2014094962-A2 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | PARP1 318/4885PRKDC 2721/4885MTOR 4657/4885 |
| US-20150318498-A1 | Metal Complexes | SOD1, AP1M1, AP3M1 | PARP1 1422/4885PRKDC 3860/4885MTOR 4584/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | PARP1 1151/4885PRKDC 3329/4885MTOR 4597/4885 |
| US-20180226591-A1 | ELECTROLUMINESCENT BRIDGED METAL COMPLEXES FOR USE IN ELECTRONIC DEVICES | EED, SOD1, NBAS | PARP1 1562/4885PRKDC 4246/4885MTOR 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.