Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 7/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15829323 | 0.80 | PARP1 (0.50) | HSD17B10HPGDALDH1A1KDM4ENPC1 | |
| SCHEMBL19794407 | 0.75 | PRKDC (0.33) | ALDH1A1PRKDCMAPTMTOR | |
| SCHEMBL19794406 | 0.74 | ALDH1A1 (0.35) | ALDH1A1KDM4EPRKDCPARP1MAPT | |
| SCHEMBL15829531 | 0.72 | MAPT (0.47) | HSD17B10HPGDALDH1A1KDM4ERAB9A | |
| SCHEMBL18015485 | 0.72 | PRMT5 (0.39) | TP53PRKDCPARP1MTOR | |
| SCHEMBL23956299 | 0.71 | PRKDC (0.31) | PRKDC | |
| SCHEMBL19794408 | 0.70 | HSD11B1 (0.40) | ALDH1A1 | |
| SCHEMBL15829532 | 0.70 | PARP1 (0.41) | ALDH1A1KDM4ENPC1RAB9ATP53 | |
| SCHEMBL14127737 | 0.68 | KDM4E (0.40) | HPGDALDH1A1KDM4ENPC1SMN1; SMN2 | |
| SCHEMBL23956213 | 0.68 | ALDH1A1 (0.32) | ALDH1A1PRKDCMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | HSD17B10 4365/4885HPGD 4368/4885ALDH1A1 2742/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | HSD17B10 3378/4885HPGD 4429/4885ALDH1A1 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.