Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.84 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510065 | 0.92 | LTA4H (1.00) | LTA4HTTRNR1H2TSHRFFAR1 | |
| SCHEMBL1744936 | 0.92 | LTA4H (1.00) | LTA4HTTRNR1H2TSHRFFAR1 | |
| SCHEMBL28009008 | 0.90 | LTA4H (0.95) | LTA4HTTRNR1H2TSHRFFAR1 | |
| SCHEMBL28009007 | 0.90 | LTA4H (0.95) | LTA4HTTRNR1H2TSHRFFAR1 | |
| SCHEMBL29661187 | 0.86 | LTA4H (0.67) | LTA4HTTRALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL358425 | 0.86 | LTA4H (0.67) | LTA4HTTRALDH1A1SMN1; SMN2TSHR | |
| Diphenylether SCHEMBL27843672 | 0.85 | LTA4H (0.86) | LTA4HTTRALDH1A1NR1H2TSHR | |
| SCHEMBL12885428 | 0.85 | LTA4H (0.66) | LTA4HTTRALDH1A1SMN1; SMN2NR1H2 | |
| SCHEMBL17984374 | 0.85 | LTA4H (0.60) | LTA4HTTRALDH1A1SMN1; SMN2TSHR | |
| Methane SCHEMBL10579323 | 0.84 | LTA4H (0.64) | LTA4HTTRALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051229-B2 | Transition metal catalysts for C—O hydrogenolysis and hydrodeoxygenation | GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2015-06-09 | — | — | US | disclosed |
| US-20140179954-A1 | TRANSITION METAL CATALYSTS FOR C-O HYDROGENOLYSIS AND HYDRODEOXYGENATION | GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179954-A1 | TRANSITION METAL CATALYSTS FOR C-O HYDROGENOLYSIS AND HYDRODEOXYGENATION | HMOX1, HAO2, PPOX | LTA4H 2213/4885TTR 4171/4885ALDH1A1 2882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.