Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 5/20 | 0.79 |
| ▸ | PPID | Q08752 | 9/20 | 0.59 |
| ▸ | PPIG | Q13427 | 2/20 | 0.59 |
| ▸ | PPIA | P62937 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643950 | 0.88 | PPIB (1.00) | PPIBPPIDPPIGPPIAEPHX1 | |
| SCHEMBL15834714 | 0.88 | PPIB (0.62) | PPIBPPIDPPIGPPIAHDAC1 | |
| SCHEMBL12643848 | 0.86 | PPIB (1.00) | PPIBPPIDPPIGPPIAHDAC1 | |
| SCHEMBL16270327 | 0.76 | PPIB (0.79) | PPIBPPIDPPIGMEN1KMT2A | |
| SCHEMBL15832178 | 0.76 | PPIB (0.77) | PPIBPPIDPPIGPPIAEPHX2 | |
| SCHEMBL15939528 | 0.75 | PPID (0.65) | PPIBPPIDPPIGPPIAEPHX1 | |
| SCHEMBL16270317 | 0.75 | PPIB (0.80) | PPIBMEN1KMT2A | |
| SCHEMBL14617679 | 0.75 | PPIB (0.58) | PPIBPPIDPPIGPPIAHDAC1 | |
| SCHEMBL12643766 | 0.74 | PPIB (0.71) | PPIBPPIDPPIGPPIAKMT2A | |
| SCHEMBL2044119 | 0.74 | PPID (1.00) | PPIBPPIDPPIGPPIAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | FKBP3, FKBP4, FKBP5 | PPIB 51/4885PPID 73/4885PPIG 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.