Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15832155 | 0.71 | SMN1; SMN2 (0.57) | HPGDGAASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL13726832 | 0.71 | HPGD (0.60) | HPGDALDH1A1HRH3POLB | |
| SCHEMBL82814 | 0.71 | HPGD (0.60) | HPGDALDH1A1HRH3POLB | |
| SCHEMBL15832148 | 0.67 | PPIB (0.52) | HPGDEPHX2GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL15832152 | 0.65 | PPID (0.43) | GAASMN1; SMN2ALDH1A1CYP2C9POLB | |
| SCHEMBL3263478 | 0.65 | HPGD (0.60) | HPGDEPHX2GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL15832187 | 0.65 | PPID (0.42) | HPGDGAASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL15832162 | 0.64 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL15832176 | 0.64 | EPHX1 (0.46) | SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL17888300 | 0.64 | NPSR1 (0.70) | HPGDALDH1A1RAB9ACYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179687-A1 | New Inhibitors of Cyclophilins and Uses Thereof | FKBP3, FKBP4, FKBP5 | HPGD 2561/4885EPHX2 1040/4885GAA 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.