Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.33 |
| ▸ | LPL | P06858 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2622051 | 0.77 | USP30 (0.42) | AAK1FFAR1DGAT1LIPGLPL | |
| SCHEMBL12502599 | 0.76 | LIPG (0.42) | FFAR1LIPGLPLCA1CA2 | |
| SCHEMBL381301 | 0.76 | FFAR1 (0.46) | P2RX4AAK1ALDH1A1TSHRMEN1 | |
| SCHEMBL14720209 | 0.74 | AAK1 (0.36) | P2RX4AAK1MEN1HPGDKMT2A | |
| SCHEMBL21401579 | 0.73 | PLA2G1B (0.45) | AAK1ALDH1A1TSHRLIPGLPL | |
| SCHEMBL24519347 | 0.72 | LPL (0.39) | AAK1FFAR1LIPGLPLCA1 | |
| SCHEMBL1985044 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRHPGDMAPTRAB9A | |
| SCHEMBL1240538 | 0.71 | LIPG (0.47) | AAK1LIPGLPLCA1CA2 | |
| SCHEMBL14858399 | 0.70 | P4HB (0.48) | TSHRFFAR1LIPGLPLCA1 | |
| SCHEMBL2029704 | 0.70 | AAK1 (0.37) | P2RX4AAK1ALDH1A1DGAT1LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2512242-A1 | NOVEL COMPOUNDS | Glaxo Wellcome Manufacturing Pte Ltd (SG) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011075559-A1 | NOVEL COMPOUNDS | GLAXO WELLCOME MANUFACTURING PTE LTD. (SG) | 2011-06-23 | — | — | WO | disclosed |
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |