Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38687 | 0.78 | ADRA2A (0.41) | LMNAMEN1KMT2APOLBPRKCI | |
| SCHEMBL1374558 | 0.78 | PRKCI (0.44) | MEN1KMT2APRKCIKDM4EMAPT | |
| SCHEMBL12438833 | 0.74 | PARP1 (0.41) | POLBPRKCIMAPTMMP12CYP3A4 | |
| SCHEMBL15893398 | 0.74 | HTR3E (0.42) | LMNAMEN1KMT2APOLBPRKCI | |
| SCHEMBL2250400 | 0.72 | PARP1 (0.39) | LMNAMEN1KMT2APOLBPRKCI | |
| SCHEMBL1193116 | 0.70 | LMNA (0.42) | LMNAMEN1KMT2APOLBKDM4E | |
| SCHEMBL1193119 | 0.70 | PARP1 (0.39) | PRKCIKDM4EMAPTRAD52MMP12 | |
| SCHEMBL168621 | 0.69 | MEN1 (0.53) | LMNAMEN1KMT2APOLBPRKCI | |
| SCHEMBL12446804 | 0.68 | LMNA (0.53) | LMNAMEN1KMT2APOLBKDM4E | |
| SCHEMBL2254298 | 0.68 | PARP1 (0.35) | LMNAMEN1KMT2APOLBPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160197275-A1 | EMITTER HAVING A CONDENSED RING SYSTEM | MERCK PATENT GMBH (DE) | 2016-07-07 | — | — | US | disclosed |
| US-20160197275-A1 | EMITTER HAVING A CONDENSED RING SYSTEM | MERCK PATENT GMBH (DE) | 2016-07-07 | — | — | US | disclosed |
| WO-2014094965-A2 | EMITTER HAVING A CONDENSED RING SYSTEM | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |