SCHEMBL38687

SCHEMBL38687

c1cnc2c(ccc3nc[nH]c32)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 8/20 0.41
ADRA2C P18825 7/20 0.41
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 3/20 0.36
USP2 O75604 1/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 2/20 0.35
PRKCI P41743 1/20 0.35
CSNK2A2 P19784 2/20 0.34
CSNK2A1 P68400 2/20 0.34
RAB9A P51151 1/20 0.34
CSNK2B P67870 1/20 0.34
DYRK1A Q13627 1/20 0.34
CSNK2A3 Q8NEV1 1/20 0.34
RAD52 P43351 1/20 0.34
ADRA1D P25100 6/20 0.33
ADRA1A P35348 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30945080 1.00 ADRA2A (0.41) ADRA2AADRA2CMEN1KMT2AKDM4E
SCHEMBL15834705 0.78 LMNA (0.44) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL1374558 0.78 PRKCI (0.44) MEN1KMT2AKDM4EMAPTALDH1A1
SCHEMBL5571160 0.77 MAPKAPK2 (0.40) KDM4EALDH1A1CSNK2A1RAB9AHPGD
SCHEMBL35938 0.76 LMNA (0.54) KDM4EMAPTALDH1A1POLBRAB9A
SCHEMBL29382312 0.76 LMNA (0.54) KDM4EMAPTALDH1A1POLBRAB9A
SCHEMBL192176 0.76 KDM4E (0.41) MEN1KMT2AKDM4EMAPTALDH1A1
Ammonia Solution, Strong SCHEMBL29846072 0.75 LMNA (0.52) KDM4EMAPTALDH1A1POLBRAB9A
SCHEMBL28400795 0.75 LMNA (0.52) KDM4EMAPTALDH1A1POLBRAB9A
Ammonia Solution, Strong SCHEMBL27979217 0.75 LMNA (0.52) KDM4EMAPTALDH1A1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1489 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115989214-B Pigment composition, inkjet recording method, image recorded matter, and pigment compound 富士胶片株式会社 2025-02-25 CN claimed
US-20230173071-A1 TREATMENT OF MYOPIA AND OTHER OCULAR CONDITIONS USING SINGLET OXYGEN GENERATED FROM DYES ACTIVATED BY NEAR-INFRARED LIGHT CALIFORNIA INST OF TECHN (US) 2023-06-08 US claimed
EP-2758075-B1 INFLUENZA VIRUS VACCINES AND USES THEREOF ICAHN SCHOOL MED MOUNT SINAI (US) 2023-05-03 EP claimed
EP-2934581-B1 INFLUENZA VIRUS VACCINES AND USES THEREOF ICAHN SCHOOL MED MOUNT SINAI (US) 2022-09-14 EP claimed
US-20220242920-A1 IMMUNOGENIC COMPOSITION GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-08-04 US claimed
CN-113286788-A Treatment of myopia and other eye disorders using singlet oxygen 加州理工学院 2021-08-20 CN claimed
US-20200129620-A1 Treatment Of Myopia And Other Ocular Conditions Using Singlet Oxygen Generated From Dyes Activated By Near-Infrared Light CALIFORNIA INSTITUTE OF TECHNOLOGY 2020-04-30 US claimed
US-20200131370-A1 Near-Infrared Heptamethine Dyes For Generation Of Singlet Oxygen CALIFORNIA INSTITUTE OF TECHNOLOGY 2020-04-30 US claimed
US-10583188-B2 Influenza virus vaccines and uses thereof ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2020-03-10 US claimed
US-20190214577-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2019-07-11 US claimed
US-4440929-A Imidazoquinoxaline compounds USV PHARMACEUTICAL CORPORATION (US) 1984-04-03 US claimed
US-4375508-A ACETHYLENIC HYDROCARBON CHAIN EASTMAN KODAK COMPANY (US) 1983-03-01 US claimed
EP-0070518-A2 Imidazoquinoxaline compounds RORER INTERNATIONAL (OVERSEAS) INC. (US) 1983-01-26 EP claimed
US-4254123-A FOR TREATMENT OF ASTHMA; ANTIALLERGENS ROUSSEL UCLAF (FR) 1981-03-03 US claimed
US-4254198-A Electrophotosensitive materials for migration imaging processes EASTMAN KODAK COMPANY (US) 1981-03-03 US claimed
US-4166740-A CYANINE DYES EASTMAN KODAK COMPANY (US) 1979-09-04 US claimed
US-RE29930-E HIGH SPEED EASTMAN KODAK COMPANY (US) 1979-03-13 US claimed
US-4108667-A Photographic compositions and elements containing benzo[a]quinolizinium methine dyes EASTMAN KODAK COMPANY (US) 1978-08-22 US claimed
US-RE29575-E Cubic regular grain photographic reversal emulsions EASTMAN KODAK COMPANY (US) 1978-03-14 US claimed
US-3935010-A IMIDAZOQUINOXALINE DESENSITIZER EASTMAN KODAK COMPANY (US) 1976-01-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220242920-A1 IMMUNOGENIC COMPOSITION HIRA, HSPA1A, HSPA8 ADRA2A 4133/4885ADRA2C 4645/4885MEN1 4372/4885
US-20190214577-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL, POLYMER, MIXTURE, FORMULATION, AND ORGANIC ELECTRONIC DEVICE TEAD2, TEAD3, TEAD1 ADRA2A 2703/4885ADRA2C 3436/4885MEN1 4137/4885
US-20200129620-A1 Treatment Of Myopia And Other Ocular Conditions Using Singlet Oxygen Generated From Dyes Activated By Near-Infrared Light CRY1, MYH10, MYLK ADRA2A 423/4885ADRA2C 985/4885MEN1 716/4885
US-20230173071-A1 TREATMENT OF MYOPIA AND OTHER OCULAR CONDITIONS USING SINGLET OXYGEN GENERATED FROM DYES ACTIVATED BY NEAR-INFRARED LIGHT CRY1, MYH10, MYLK ADRA2A 423/4885ADRA2C 985/4885MEN1 716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.